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Product Name
Ionomycin
Catalog #
SIH-228-5MG
Size
5mg
Price
$288.00 USD
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Alternate Product Sizes
SIH-228-1MG
Type
Inducer
Datasheet
SIH 228 Ionomycin Apoptosis Inducer
Description
Ca2+ ionophore
Research Area
Apoptosis
Alternative Names
Ionomycin calcium salt
CAS Number
56092-81-0
Formula
C41H72O9
Molecular weight
709.01
Source/Host
Synthetic
Purity
>99%
Solubility
Soluble to 10mM in ethanol and to 10mM in DMSO
Appearance
Colorless solid
Safety Phrases
Classification: Caution: Substance not yet fully tested.

Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases:
H303
Storage Temp
-20°C
Shipping Temp
Blue Ice or 4°C

Structure of Ionomycin
Research Background
Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187.
References
1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495.
2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112.
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