Small Molecules - Apoptosis, Cellular Oxidative Stress,

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Product Name: Cycloheximide
Catalog #: SIH-247-5G
Size: 5g
Price: $135.00 USD

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Alternate Product Sizes: SIH-247-1G
Type: Inducer
Datasheet: SIH 247 Cycloheximide Apoptosis Inducer
Description: Translation inhibitor
Research Area: Apoptosis
CAS Number: 66-81-9
Formula: C15H23NO4
Molecular weight: 281.35
Source/Host: Synthetic
Purity: >99%
Solubility: Soluble to 50mM in Ethanol and 25mM in water.
Appearance: White solid
Safety Phrases: Classification: Very toxic. May be fatal if inhaled, swallowed or absorbed through skin.

Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)

Risk Phrases:
R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed
R62 - Possible risk of impaired fertility
R68- Possible risk of irreversible effects

Hazard Phrases:
H300-H341-H360D-H411

Precautionary Phrases:
P201-P264-P273-P281-P301 + P310-P308 + P313
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C

Structure for Cycloheximide

Research Background: Selective inhibitor of eukaryotic protein synthesis blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T-cells.
References: 1. Obrig T.G., et al. (1971) J Biol Chem. 246:174.

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