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Product Name: WP-1130
Catalog #: SIH-337-5MG
Size: 5mg
Price: $125.00 USD

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Alternate Product Sizes: SIH-337-25MG
Type: Inhibitor
Datasheet: SIH 337 WP 1130 Apoptosis Inhibitor
Description: DUB Inhibitor
Research Area: Apoptosis
CAS Number: 856243-80-6
Formula: C19H18BrN30
Molecular weight: 384.3
Source/Host: Synthetic
Purity: >98% (TLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (45mg/mL) or Ethanol (25mg/mL)
Appearance: Pale Yellow Powder
Safety Phrases: Classification: Caution – Substance not yet fully tested.

Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with skin and eyes
Storage Temp: -20°C
Shipping Temp: Blue Ice or 4°C

Research Background: A novel DUB inhibitor directly inhibiting USP9x, USP5, USP14 and UCH37 inducing rapid accumulation of polyubiquitinated proteins. Blocks Jak2 signaling via Jak2 ubiquitination.
References: 1. KapuriaV., et al. (2010) Cancer Res. 70:9265.
2. Kapuria V., et al. (2011) Cell Signal. 23:2076.

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