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| Product Name | GDC 0941 |
| Description |
pan-PI3K kinase inhibitor |
| Purity | >98% |
| CAS No. | 957054-30-7 |
| Molecular Formula | C23H27N7O3S2 |
| Molecular Weight | 513.63 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO |
| Source | Synthetic |
| Appearance | White solid |
| SMILES | CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6 |
| InChI | InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27) |
| InChIKey | LHNIIDJUOCFXAP-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | GDC 0941 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-501) |
Biological Description
| Alternative Names | Pictrelisib, Pictilisib, GNE 0941, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 17755052 |
| Scientific Background | GDC 0941 is a potent inhibitor of the PI 3-kinase family. Specifically, GDC 0941 has been shown to inhibit PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ. |
| References | 1. Zheng J., Wang H., Yao J., & Zou X. (2014) Die Pharmazie. 69(1): 38–42. |
Product Images
Chemical structure of GDC 0941 (SIH-501), a pan-PI3K kinase inhibitor. CAS #: 957054-30-7. Molecular Formula: C23H27N7O3S2. Molecular Weight: 513.63 g/mol.
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