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| Product Name | TG003 |
| Description |
Clk family kinase inhibitor |
| Purity | >98% |
| CAS No. | 719277-26-6 |
| Molecular Formula | C13H15NO2S |
| Molecular Weight | 249.3 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 100 mM in DMSO and to 75 mM in ethanol |
| Source | Synthetic |
| Appearance | Yellow solid |
| SMILES | CCN1C2=C(C=CC(=C2)OC)S/C1=CC(=O)C |
| InChI | InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7- |
| InChIKey | BGVLELSCIHASRV-QPEQYQDCSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | TG003 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-515) |
Biological Description
| Alternative Names | TG 003, (1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 1893668 |
| Scientific Background | TG003 is a potent inhibitor of the CDC-like (Clk) family kinases. It has been shown to suppress serine/arginine-rich protein phosphorylation. |
| References | 1. Muraki M., et al. (2004) J. Biol. Chem. 279(23): 24246–24254. |
Product Images
Chemical structure of TG003 (SIH-515), a Clk family kinase inhibitor. CAS #: 719277-26-6. Molecular Formula: C13H15NO2S. Molecular Weight: 249.3 g/mol.
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