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| Product Name | 6-Formylindolo(3,2-b)carbazole |
| Description |
Ah receptor ligand |
| Purity | >95% |
| CAS No. | 172922-91-7 |
| Molecular Formula | C19H12N2O |
| Molecular Weight | 284.3 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Ligand |
| Solubility | Soluble in DMSO (10 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow solid |
| SMILES | C1=CC=C2C(=C1)C3=CC4=NC5=CC=CC=C5C4=C(C3=N2)C=O |
| InChI | InChI=1S/C19H10N2O/c22-10-14-18-12-6-2-4-8-16(12)20-17(18)9-13-11-5-1-3-7-15(11)21-19(13)14/h1-10H |
| InChIKey | OTWFDHQTFRXSAK-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution. Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25 - Avoid contact with skin and eyes |
| Cite This Product | 6-Formylindolo(3,2-b)carbazole (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-383) |
Biological Description
| Alternative Names | Indolo[3,2-b]carbazole-6-carbaldehyde, FICZ |
| Research Areas | Cell Signaling |
| PubChem ID | 22245026 |
| Scientific Background | A tryptophan-derived, high affinity aryl hydrocarbon receptor ligand (Kd=7x10-11 M). Proposed to be an endogenous AhR ligand. Induces rapid and transient expression of cytochrome P450-1A1 (CYP1A1) in human cells at 100 pM. |
| References |
1. Wei Y.D., et al. (1998) Chem. Biol. Interact. 110(1-2): 39-55. 2. Rannug U., et al. (1995) Chem. Biol. Drug. Des. 2(12): 841-855. 3. Rannug A., et al. (1987) J. Biol. Chem. 262(32): 15422-7. |
Product Images
Chemical structure of 6-Formylindolo(3,2-b)carbazole (SIH-383), a Ah receptor ligand. CAS #: 172922-91-7. Molecular Formula: C19H12N2O. Molecular Weight: 284.3 g/mol.
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