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| Product Name | Anisomycin |
| Description |
p38 MAP kinase activator |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Appearance | White solid |
| Safety Phrases |
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed Hazard Phrases: H301 Precautionary Phrases: P301 + P310 |
| Cite This Product | Anisomycin (StressMarq Biosciences, Canada, Cat # SIH-266) |
Biological Description
| Alternative Names | (2S,3R,4R)-4-Hydroxy-2-(4-methoxybenzyl)-3-pyrrolidinyl acetate |
| Scientific Background | Anisomycin is an antibiotic which inhibits protein synthesis (1). It interferes with protein and DNA synthesis by inhibiting peptidyl transferace on the 80S ribosome system. It can activate stress-activated protein kinases, MAPkinase and other signal transduction pathways. |
| References | 1. Grollman A.P. (1967) J Biol Chem. 242(13): 3226-3233. |
Product Images
Chemical structure of Anisomycin (SIH-266), a Anoikis sensitizer. CAS #: 22862-76-6. Molecular Formula: C14H19NO4 . Molecular Weight: 265.31 g/mol.
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Based on validation through cited publications.