Product Name | Veratridine |
Description |
Na channel activator |
Purity | >98% |
CAS No. | 71-62-5 |
Molecular Formula | C36H51NO11 |
Molecular Weight | 673.79 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Activator |
Solubility | Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml) |
Source | Synthetic |
Appearance | White solid |
SMILES | C[C@H]1CC[C@H]2[C@@]([C@]3([C@H](C[C@]4([C@@H]5CC[C@H]6[C@]7([C@]5(C[C@]4([C@@H]3CN2C1)O)O[C@@]6([C@H](CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O |
InChI | InChI=1S/C36H51NO11/c1-19-6-11-26-31(3,40)35(43)25(17-37(26)16-19)33(42)18-34-24(32(33,41)15-27(35)38)10-9-23-30(34,2)13-12-28(36(23,44)48-34)47-29 |
InChIKey | FVECELJHCSPHKY-UIHGVQCZSA-N |
Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302-H315-H317-H318-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338 |
Cite This Product | Veratridine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-300) |
Alternative Names | (3β,4α,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3-yl 3,4-dimethoxybenzoate |
Research Areas | Ion Channels, Neuroscience, Sodium Channels |
PubChem ID | 6280 |
Scientific Background | Veratridine is a steroid-derived alkaloid that functions as a neurotoxin by activating sodium channels. It binds to intramembrane receptor site 2 thereby increasing intracellular Ca2+ concentration. |
References | 1. Sperelakis N., Pappano A.J. (1969) J Gen Physiol. 53(1): 97-114. |
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