Apomorphine HCl Hydrate

Dopamine Agonist

Catalog No. SIH-619

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CAS No. 41372-20-7
Molecular Formula C17H17NO2 • HCl ½H2O
SKU: SIH-619 Categories: ,

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SIH-619-Apomorphine-HCl-Hydrate-Chemical-Structure
Product Name Apomorphine HCl Hydrate
Description

Dopamine Agonist

Purity >98% (TLC); NMR (Conforms)
CAS No. 41372-20-7
Molecular Formula C17H17NO2 • HCl ½H2O
Molecular Weight 312.8
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Agonist
Solubility May be dissolved in water (20 mg/ml)
Source Synthetic
Appearance Gray Powder
SMILES CN1CCC2=C3C1CC4=C(C3=CC=C2)C(=C(C=C4)O)O.Cl
InChI InChI=1S/C17H17NO2.ClH/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;/h2-6,13,19-20H,7-9H2,1H3;1H/t13-;/m1./s1
InChIKey SKYZYDSNJIOXRL-BTQNPOSSSA-N
Safety Phrases Classification: Danger.

Hazard Statements: H301
Precautionary Statements: P301 + P310 + P330
Cite This Product Apomorphine HCl Hydrate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-619)

Biological Description

Alternative Names Hemihydrate; R-(-)-6ab-aporphine-10,11-diol, hydrochloride; (R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol, hydrochloride
Research Areas Neurodegeneration, Neuroscience, Parkinson's Disease
PubChem ID 9410
Scientific Background Archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo (1,2). Protects against MPTP-induced neurotoxicity in a mouse model (3). In clinical use for Parkinson’s disease (4,5).
References 1. Merck Index 14:746
2.Millan M.J., et al. (2002) J. Pharmacol. Exp. Ther. 303:791.
3. Grunblatt E., et al. (1999) Mov. Disord. 1999 14:612.
4. Auffret M., et al.( 2017) J. Neurol. Sci. 372:279.
5. Jenner P.and R Katzenschlager ( 2016) Parkinsonism. Relat. Disord. 33 Suppl 1:S13.

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