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| Product Name | Bexarotene |
| Description |
Retinoid RXR agonist |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 153559-49-0 |
| Molecular Formula | C24H28O2 |
| Molecular Weight | 348.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Agonist |
| Solubility | Soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml) |
| Source | Synthetic |
| Appearance | White powder |
| SMILES | Cc1cc2c(cc1C(=C)c3ccc(cc3)C(=O)O)C(CCC2(C)C)(C)C |
| InChI | InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26) |
| InChIKey | NAVMQTYZDKMPEU-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Bexarotene (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-535) |
Biological Description
| Alternative Names | SR 11247, Targretin, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid |
| Research Areas | Cancer, Cancer Growth Inhibitors, Cell Signaling, Neurodegeneration, Neuroscience, Nuclear Signaling Pathways |
| PubChem ID | 82146 |
| Scientific Background | Bexarotene is a potent RXR agonist. It is able to permeate the blood-brain barrier. Bexarotene inhibits neurodegeneration and has anti-tumor properties. |
Product Images
Chemical structure of Bexarotene (SIH-535), a Retinoid RXR agonist. CAS #: 153559-49-0. Molecular Formula: C24H28O2. Molecular Weight: 348.5 g/mol.
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