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| Product Name | BzATP |
| Description |
Prototypic P2X7 receptor agonist |
| Purity | 97.7% |
| CAS No. | 112898-15-4 |
| Molecular Formula | C24H24N5O15P3•C18H45N3 |
| Molecular Weight | 1018.97 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Agonist |
| Solubility | Soluble in water. |
| Source | Synthetic |
| Appearance | Off white solid |
| SMILES | [C@H]3(O[C@@H]([C@@H](OC(=O)C1=CC=C(C=C1)C(=O)C2=CC=CC=C2)[C@H]3O)CO[P](O[P](O[P](=O)(O)O)(=O)O)(=O)O)[N]4C5=C(N=C4)C(=NC=N5)N |
| InChI | InChI=1S/C24H24N5O15P3.C6H15N/c25-21-17-22(27-11-26-21)29(12-28-17)23-19(31)20(16(41-23)10-40-46(36,37)44-47(38,39)43-45(33,34)35)42-24(32)15-8-6-14(7-9-15)18(30)13-4-2-1-3-5-13;1-4-7(5-2)6-3/h1-9,11 |
| InChIKey | HVOVBTNCGADRTH-WBLDMZOZSA-N |
| Safety Phrases |
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | BzATP (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-420) |
Biological Description
| Alternative Names | 2'(3')-O-(4-Benzoylbenzoyl)adenosine-5'-triphosphate tri(triethylammonium) salt |
| Research Areas | Ion Channels, Neuroscience |
| PubChem ID | 71308559 |
| Scientific Background | BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP. This small molecule also exhibits partial agonist activity at P2X1 and P2Y1 receptors. Lastly, it can be used as a photoaffinity label for ATPase. |
| References | 1. Young M., Pelegrin P., & Surprenant A. (2007) Mol Pharmacol. 92-100. |
Product Images
Chemical structure of BzATP (SIH-420), a Prototypic P2X7 receptor agonist. CAS #: 112898-15-4. Molecular Formula: C24H24N5O15P3.C18H45N3. Molecular Weight: 1018.97 g/mol.
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