Product Name | Kainic acid |
Description |
Kainate agonist |
Purity | >99% (HPLC) |
CAS No. | 58002-62-3 |
Molecular Formula | C10H15NO4•H2O |
Molecular Weight | 213.2 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Agonist |
Solubility | May be dissolved in water (10 mg/ml) |
Source | Synthetic |
Appearance | White powder |
SMILES | CC(=C)[C@H]1CN[C@@H]([C@H]1CC(=O)O)C(=O)O |
InChI | InChI=1S/C10H15NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h6-7,9,11H,1,3-4H2,2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1 |
InChIKey | VLSMHEGGTFMBBZ-OOZYFLPDSA-N |
Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
Cite This Product | Kainic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-364) |
Alternative Names | (2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-pyrrolidine-2-carboxylic acid, Monohydrate |
Research Areas | Glutamate Receptors, Ion Channels, Kainate Receptors, Neuroscience, Neurotransmitter Receptors |
PubChem ID | 10255 |
Scientific Background | Kainic acid is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. It is a central nervous system stimulant and neurotoxin. It acts as a classic neuroexcitatory agent for induction of seizures in laboratory animals (typical dose 10-30 mg/kg). |
References | 1. Watkins J.C., et al. (1981) Ann. Rev. Pharmacol. Toxicol. 21: 165. |
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