Biotinyl Tyramide

Signal Amplifier

Catalog No. SIH-573

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CAS No. 41994-02-9
Molecular Formula C18H25N3O3S
SKU: SIH-573 Categories: ,

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SIH-573-Biotinyl-Tyramide-Chemical-Structure.png
Product Name Biotinyl Tyramide
Description

Signal Amplifier

Purity >98% (TLC); NMR (Conforms)
CAS No. 41994-02-9
Molecular Formula C18H25N3O3S
Molecular Weight 363.5
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Amplifier
Solubility May be dissolved in DMSO (35 mg/ml); or ethanol (20 mg/ml)
Source Synthetic
Appearance White powder
SMILES [H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(NCCC3=CC=C(C=C3)O)=O
InChI InChI=1S/C18H25N3O3S/c22-13-7-5-12(6-8-13)9-10-19-16(23)4-2-1-3-15-17-14(11-25-15)20-18(24)21-17/h5-8,14-15,17,22H,1-4,9-11H2,(H,19,23)(H2,20,21,24)/t14-,15-,17-/m0/s1
InChIKey VZWXNOBHWODXCW-ZOBUZTSGSA-N
Safety Phrases Classification:
Not a hazardous substance or mixture.

Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product Biotinyl Tyramide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-573)

Biological Description

Alternative Names (3aS,4S,6aR)-Hexahydro-N-[2-(4-hydroxyphenyl)ethyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; Biotin-phenol
Research Areas Cell Signaling, Neuroscience
PubChem ID 21826423
Scientific Background Biotinyl Tyramide is a biotin derivative that can be used as a reagent to amplify both IHC signals and in situ hybridization protocols (1). The secondary should be an HRP-labelled antibody or streptavidin conjugate; catalysis by the HRP results in the deposition of multiple tyramide molecules which can then be detected with a labeled streptavidin conjugate. Sensitivity has found to be 100 fold. It can be used with both chromogenic and fluorescent visualization methods (2).
References 1. Bobrow M.N. et al., (1989) J. Immunol. Methods. 125:279. 2. Kim S.H., et al. (2003) J Histochem Cytochem. 51(1): 129-132.

Product Images

<p>Chemical structure of Biotinyl Tyramide (SIH-573), a Signal Amplifier. CAS #: 41994-02-9. Molecular Formula: C18H25N3O3S. Molecular Weight: 363.47 g/mol.</p>

Chemical structure of Biotinyl Tyramide (SIH-573), a Signal Amplifier. CAS #: 41994-02-9. Molecular Formula: C18H25N3O3S. Molecular Weight: 363.47 g/mol.

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