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| Product Name | Aripiprazole |
| Description |
Dopamine D2 receptor antagonist. |
| Purity | 98% (TLC); NMR (Conforms) |
| CAS No. | 129722-12-9 |
| Molecular Formula | C23H27Cl2N3O2 |
| Molecular Weight | 448.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Antagonist |
| Solubility | May be dissolved in DMSO (30 mg/ml); or ethanol (5 mg/ml, warm) |
| Source | Synthetic |
| Appearance | White powder |
| SMILES | C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl |
| InChI | InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) |
| InChIKey | CEUORZQYGODEFX-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Danger GHS Hazard Statements, H301 (62.7%): Toxic if swallowed [Danger Acute toxicity, oral] H302 (35.3%): Harmful if swallowed [Warning Acute toxicity, oral] H361 (15.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity] H413 (13.7%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Precautionary Statement Codes,: P203, P264, P270, P273, P280, P301+P316, P301+P317, P318, P321, P330, P405, and P501 |
| Cite This Product | Aripiprazole (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-630) |
Biological Description
| Alternative Names | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone; OPC-14597 |
| Research Areas | Alzheimer's Disease, Neurodegeneration, Neuroscience |
| PubChem ID | 60795 |
| Scientific Background | Clinically useful neuroleptic and antipsychotic agent1. Dopamine D2 receptor antagonist and autoreceptor agonist2. Improves symptoms of psychosis associated with Alzheimer’s disease3. Blocks cocaine-seeking behavior without affecting other rewarding behaviors in animal models4 |
| References |
1.,B Green Curr. Med. Res. Opin. 2004 20:207 2.,T Kikuchi et al. J. Pharmacol. Exp. Ther. 1995 274:329 3.,S Madhusoodanan et al. Clin. Interv. Aging. 2008 3:491 4.,MW Feltenstein et al. Biol. Psychiatry 2007 61:582 |
Product Images
Chemical structure of Aripiprazole (SIH-630), a Dopamine D2 receptor antagonist. . CAS #: 129722-12-9. Molecular Formula: C23H27Cl2N3O2. Molecular Weight: 448.4 g/mol.
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