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| Product Name | Clozapine |
| Description |
Dopamine receptor antagonist |
| Purity | >98% (TLC); NMR (Conforms) |
| CAS No. | 5786-21-0 |
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.8 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Antagonist |
| Solubility | Soluble in DMSO (30 mg/ml) |
| Source | Synthetic |
| Appearance | Yellow powder |
| SMILES | CN1CCN(CC1)C2=C3C=CC=CC3=Nc4ccc(Cl)cc4N2 |
| InChI | 1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 |
| InChIKey | ZUXABONWMNSFBN-UHFFFAOYSA-N |
| Safety Phrases |
Classification: D1B Toxic Material Causing Immediate and Serious Toxic Effects - Toxic by ingestion D2A Very Toxic Material Causing Other Toxic Effects - Teratogen D2B Toxic Material Causing Other Toxic Effects - Carcinogen, Moderate eye irritant, Mutagen Hazard statement(s): H301 Toxic if swallowed. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H361 Suspected of damaging fertility or the unborn child. Precautionary statement(s): P281 Use personal protective equipment as required. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. |
| Cite This Product | Clozapine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-541-250MG) |
Biological Description
| Alternative Names | 3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[c][1,5]benzodiazepine, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]-diazepine, Clozapine, Leponex, Clozapin, CLOZARIL, Fazaclo |
| Research Areas | Neuroscience, Neurotransmitter Receptors |
| PubChem ID | 2818 |
| Scientific Background | Clozapine is a atypical antipsychotic. It binds several types of receptors in the brain, and acts as a serotonin antagonist. Predicted to act through 5-HT 2A/2C and dopamine receptor blockade. |
Product Images
Chemical structure of Clozapine (SIH-541), a Dopamine receptor antagonist. CAS #: 5786-21-0. Molecular Formula: C18H19ClN4. Molecular Weight: 326.8 g/mol.
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