Product Name | D-AP5.Na |
Description |
NMDA receptor antagonist |
Purity | >99.5 |
CAS No. | 14375-45-2 |
Molecular Formula | C5H12NO5P.Na |
Molecular Weight | 219.11 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Antagonist |
Solubility | Soluble in 1 M NH4OH (50 mg/ml); water (9 mg/ml). |
Source | Synthetic |
Appearance | White solid |
SMILES | [C@@H]([NH3+])(CCC[P]([O-])([O-])=O)C([O-])=O |
Safety Phrases |
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
Cite This Product | D-AP5.Na (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-412) |
Alternative Names | D-amino-5-phosphonopentaoic acid sodium salt |
Research Areas | Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors, NMDA Receptors |
Scientific Background | DAP5 is used widely as a potent and selective NMDA receptor antagonist. It represents the active enantiomer form of AP5 (2-amino-5-phosphonopentanoic acid). |
References |
1. Davies J., & Watkins J. (1982) Brain Res. 378-86. 2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7. |
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