D-AP5

NMDA receptor antagonist

Catalog No. SIH-411

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CAS No. 79055-68-8
Molecular Formula C5H12NO5P
SKU: SIH-411 Categories: ,

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SIH-411_DAP5_Chemical_Structure.png
Product Name D-AP5
Description

NMDA receptor antagonist

Purity >99.5
CAS No. 79055-68-8
Molecular Formula C5H12NO5P
Molecular Weight 197.13
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antagonist
Solubility Soluble in 100 mM water
Source Synthetic
Appearance White solid
SMILES [C@@H]([NH3+])(CCC[P]([O-])([O-])=O)C([O-])=O
InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/t4-/m1/s1
InChIKey VOROEQBFPPIACJ-SCSAIBSYSA-N
Safety Phrases Classification: D2B Toxic Material Causing Other Toxic Effects, Moderate skin irritant, Moderate respiratory irritant, Moderate eye irritant
Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statements:
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Cite This Product D-AP5 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-411)

Biological Description

Alternative Names D-amino-5-phosphonopentaoic acid
Research Areas Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors, NMDA Receptors
PubChem ID 135342
Scientific Background DAP5 is used widely as a potent and selective NMDA receptor antagonist. It represents the active enantiomer form of AP5 (2-amino-5-phosphonopentanoic acid).
References 1. Davies J., & Watkins J. (1982) Brain Res. 378-86.
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.

Product Images

<p>Chemical structure of D-AP5 (SIH-411), a Glutamate-NMDA receptor antagonist. CAS #: 79055-68-8. Molecular Formula: C5H12NO5P. Molecular Weight: 197.13 g/mol.</p>

Chemical structure of D-AP5 (SIH-411), a Glutamate-NMDA receptor antagonist. CAS #: 79055-68-8. Molecular Formula: C5H12NO5P. Molecular Weight: 197.13 g/mol.

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