D-LAP5

NMDA receptor antagonist

Catalog No. SIH-413

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CAS No. 76326-31-3
Molecular Formula C5H12NO5P
SKU: SIH-413 Categories: ,

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SIH-413_DLAP5_Chemical_Structure.png
Product Name D-LAP5
Description

NMDA receptor antagonist

Purity >99.0
CAS No. 76326-31-3
Molecular Formula C5H12NO5P
Molecular Weight 197.13
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Antagonist
Solubility Soluble to 10 mM in water and to 100 mM in 1eq. NaOH
Source Synthetic
Appearance White solid
SMILES C([P](O)(O)=O)CCC(C(O)=O)N
InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChIKey VOROEQBFPPIACJ-UHFFFAOYSA-N
Safety Phrases Classification: D2B Toxic Material Causing Other Toxic Effects, Moderate skin irritant, Moderate respiratory irritant, Moderate eye irritant
Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary statements:
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/ eye protection/ face protection.
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Cite This Product D-LAP5 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-413)

Biological Description

Alternative Names DL-amino-5-phosphonopentaoic acid
Research Areas Glutamate Receptors, Ion Channels, Neuroscience, Neurotransmitter Receptors, NMDA Receptors
PubChem ID 1216
Scientific Background DLAP5 is a racemic mixture. It is used widely as a potent and selective NMDA receptor antagonist. It represents the active enantiomer form of AP5 (2-amino-5-phosphonopentanoic acid).
References 1. Davies J., & Watkins J. (1982) Brain Res. 378-86.
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.

Product Images

<p>Chemical structure of D-LAP5 (SIH-413), a Glutamate-NMDA receptor antagonist. CAS #: 76326-31-3. Molecular Formula: C5H12NO5P. Molecular Weight: 197.13 g/mol.</p>

Chemical structure of D-LAP5 (SIH-413), a Glutamate-NMDA receptor antagonist. CAS #: 76326-31-3. Molecular Formula: C5H12NO5P. Molecular Weight: 197.13 g/mol.

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