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| Product Name | Montelukast sodium |
| Description |
Leukotriene CysLT1 antagonist |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 151767-02-1 |
| Molecular Formula | C35H35ClNO3S • Na |
| Molecular Weight | 608.2 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Antagonist |
| Solubility | Soluble in DMSO (50 mg/ml), or water (30 mg/ml), or ethanol (60 mg/ml) |
| Source | Synthetic |
| Appearance | Powder |
| SMILES | CC(C)(O)C(C=CC=C1)=C1CC[C@H](SCC2(CC2)CC([O-])=O)C3=CC(/C=C/C4=NC5=CC(Cl)=CC=C5C=C4)=CC=C3.[Na+] |
| InChI | 1S/C35H36ClNO3S.Na/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,( |
| InChIKey | LBFBRXGCXUHRJY-YBGTYPRZSA-M |
| Safety Phrases |
Classification: D2A Very Toxic Material Causing Other Toxic Effects - Reproductive hazard E Corrosive Material - Corrosive to skin Hazard statement(s): H318 Causes serious eye damage. H361fd Suspected of damaging fertility. Suspected of damaging the unborn child. Precautionary statement(s): P280 Wear protective gloves/ eye protection/ face protection. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Cite This Product | Montelukast sodium (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-538) |
Biological Description
| Alternative Names | 1-[[[(1R)-1-[3-(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]-methyl]-cyclopropaneacetic acid, monosodium salt, Montelukast sodium, Montelukast monosodium salt, MK-0476, MK-476, KS-1087 |
| Research Areas | Immunology, Innate Immunity, Macrophage |
| PubChem ID | 23663996 |
| Scientific Background | Montelukast is a cysteinyl leukotriene receptor 1 (CysLT1) antagonist. It blocks pentylenetetrazole-induced seizures, blood brain barrier disruption and leukocyte migration in mice. |
Product Images
Chemical structure of Montelukast sodium (SIH-538), a Leukotriene CysLT1 antagonist. CAS #: 151767-02-1. Molecular Formula: C35H35ClNO3S • Na. Molecular Weight: 608.2 g/mol.
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