Product Name | Z-Guggulsterone |
Description |
FXR Antagonist |
Purity | >98% (TLC); NMR (Conforms) |
CAS No. | 39025-23-5 |
Molecular Formula | C21H28O2 |
Molecular Weight | 312.5 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Antagonist |
Solubility | May be dissolved in DMSO (6 mg/ml, warm); or Ethanol (3 mg/ml, warm) |
Source | Synthetic |
Appearance | Off-white powder |
SMILES | CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C |
InChI | InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1 |
InChIKey | WDXRGPWQVHZTQJ-OSJVMJFVSA-N |
Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
Cite This Product | Z-Guggulsterone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-591) |
Alternative Names | (Z)-Pregna-4,17(20)-diene-3,16-dione |
Research Areas | Apoptosis, Cancer |
PubChem ID | 6450278 |
Scientific Background | Z-Guggulsterine acts as a selective antagonist at farnesoid X receptors, and inhibits FXR transactivation. It is also a retinoic acid receptor (RAR) pathway inhibitor. |
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