Product Name | Oleamide |
Description |
Endogenous Sleep-inducing Lipid |
Purity | >99% (TLC); NMR (Conforms) |
CAS No. | 301-02-0 |
Molecular Formula | C18H35NO |
Molecular Weight | 281.5 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Inducer |
Solubility | May be dissolved in DMSO (25 mg/ml); or Ethanol (40 mg/ml) |
Source | Synthetic |
Appearance | White to off-white powder |
SMILES | CCCCCCCCC=CCCCCCCCC(=O)N |
InChI | InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9- |
InChIKey | FATBGEAMYMYZAF-KTKRTIGZSA-N |
Safety Phrases |
Classification: Warning GHS Hazard Statements,: H315, H317, H319, H335, H413 Precautionary Statement Codes,: P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Cite This Product | Oleamide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-627) |
Alternative Names | 9Z-Octadecenamide; cis-9-Octadecenamide; Oleic acid amide |
Research Areas | Neuroscience, Neurotransmission, Neurotransmitter Receptors |
PubChem ID | 5283387 |
Scientific Background | Originally identified in the cerebrospinal fluid of sleep-deprived cats acting as an inducer of physiological sleep in animals (1). Displays agonist activity at cannabinoid CB1 receptors (Ki=8.13 µM) (2). Activates PPARΥ (3). Produces vasodilator effects in rats (4). Displays neuroprotective effects (5) and attenuates sepsis-induced intestinal injury (6). |
References |
1.,DL Boger et al. 1998 Curr. Pharm. Des. 4:303. 2.,JD Leggett et al. 2004 Br. J. Pharmacol. 141:253. 3.,M Dionisi et al. 2012 Lipids Health Dis. 11:51. 4.,C Hernandez-Diaz et al. 2020 Cannabis Cannabinoid Res. 5:42. 5.,M Maya-Lopez et al. 2020 Neurotox. Res. 37:126. 6.,Z Zou et al. Mediators Inflamm. 2019 2019:7854389 (eCollection 2019). |
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