Oleamide

Endogenous Sleep-inducing Lipid

Catalog No. SIH-627

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CAS No. 301-02-0
Molecular Formula C18H35NO
SKU: SIH-627 Categories: ,

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SIH-627-Oleamide-Chemical-Structure.png
Product Name Oleamide
Description

Endogenous Sleep-inducing Lipid

Purity >99% (TLC); NMR (Conforms)
CAS No. 301-02-0
Molecular Formula C18H35NO
Molecular Weight 281.5
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inducer
Solubility May be dissolved in DMSO (25 mg/ml); or Ethanol (40 mg/ml)
Source Synthetic
Appearance White to off-white powder
SMILES CCCCCCCCC=CCCCCCCCC(=O)N
InChI InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
InChIKey FATBGEAMYMYZAF-KTKRTIGZSA-N
Safety Phrases Classification: Warning
GHS Hazard Statements,: H315, H317, H319, H335, H413
Precautionary Statement Codes,: P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Cite This Product Oleamide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-627)

Biological Description

Alternative Names 9Z-Octadecenamide; cis-9-Octadecenamide; Oleic acid amide
Research Areas Neuroscience, Neurotransmission, Neurotransmitter Receptors
PubChem ID 5283387
Scientific Background Originally identified in the cerebrospinal fluid of sleep-deprived cats acting as an inducer of physiological sleep in animals (1). Displays agonist activity at cannabinoid CB1 receptors (Ki=8.13 µM) (2). Activates PPARΥ (3). Produces vasodilator effects in rats (4). Displays neuroprotective effects (5) and attenuates sepsis-induced intestinal injury (6).
References 1.,DL Boger et al. 1998 Curr. Pharm. Des. 4:303.
2.,JD Leggett et al. 2004 Br. J. Pharmacol. 141:253.
3.,M Dionisi et al. 2012 Lipids Health Dis. 11:51.
4.,C Hernandez-Diaz et al. 2020 Cannabis Cannabinoid Res. 5:42.
5.,M Maya-Lopez et al. 2020 Neurotox. Res. 37:126.
6.,Z Zou et al. Mediators Inflamm. 2019 2019:7854389 (eCollection 2019).

Product Images

<p>Chemical structure of Oleamide (SIH-627), a Endogenous Sleep-inducing Lipid. CAS #: 301-02-0. Molecular Formula: C18H35NO. Molecular Weight: 281.5 g/mol.</p>

Chemical structure of Oleamide (SIH-627), a Endogenous Sleep-inducing Lipid. CAS #: 301-02-0. Molecular Formula: C18H35NO. Molecular Weight: 281.5 g/mol.

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