AG 879

Name: AG 879
SKU: SIH-429
Availability: InStock

NGFR kinase inhibitor

Catalog No. SIH-429

0 out of 5 based on 0 customer ratings

Reviews (0) | Datasheet

CAS No.	148741-30-4
Molecular Formula	C18H24N2OS

SKU: SIH-429 Categories: Inhibitor, Small Molecules

Product Name	AG 879
Description	NGFR kinase inhibitor
Purity	99% (TLC)
CAS No.	148741-30-4
Molecular Formula	C₁₈H₂₄N₂OS
Molecular Weight	316.5
Field of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Storage Temperature	-20ºC
Shipping Temperature	Shipped Ambient
Product Type	Inhibitor
Solubility	Soluble in 100% ethanol (25 mg/ml) or DMSO (25 mg/ml)
Source	Synthetic
Appearance	Yellow solid
SMILES	CC(C1=CC(C=C(C(C)(C)C)C1=O)=CC(=C(S)N)C#N)(C)C
InChI	InChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,22H,20H2,1-6H3/b16-12+
InChIKey	LCUMYVYIHXYBIA-FOWTUZBSSA-N
Safety Phrases	Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product	AG 879 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-429)

Alternative Names	Tyrphostin AG 879, α-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide
Research Areas	Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID	5487525
Scientific Background	A879 is a selective inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. It also inhibits ErbB2 and VEGFR-2.
References	1. He H., et al. (2004) Cancer Biol. Therapy. 3(1): 96–101. 2. Ohmichi M., et al. (1993) Biochem. 32(17): 4650–4658.

Chemical structure of AG 879 (SIH-429), a NGFR kinase inhibitor. CAS #: 148741-30-4. Molecular Formula: C18H24N2OS. Molecular Weight: 316.5 g/mol.

There are no reviews yet.

Be the first to review “AG 879”