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| Product Name | AG1296 |
| Description |
PDGFR kinase inhibitor |
| Purity | >98% (TLC) |
| CAS No. | 146535-11-7 |
| Molecular Formula | C16H14N2O2 |
| Molecular Weight | 266.3 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO or dichloromethane |
| Source | Synthetic |
| Appearance | Off-white to brownish solid |
| SMILES | C1=C(OC)C(=CC2=NC=C(N=C12)C3=CC=CC=C3)OC |
| InChI | InChI=1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3 |
| InChIKey | QNOXYUNHIGOWNY-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | AG1296 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-426) |
Biological Description
| Alternative Names | Tyrphostin AG 1296, 6,7-Dimethoxy-3-phenylquinoxaline, 6,7-Dimethoxy-2-phenylquinoxaline |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 2049 |
| Scientific Background | AG-1296 is a potent and specific inhibitor of PDGF receptor tyrosine kinase. AG-1296 is cell-permeable. |
| References | 1. Strutz F., et al. (2001) Kidney Int. 59(2): 579–592. |
Product Images
Chemical structure of AG1296 (SIH-426), a PDGFR kinase inhibitor. CAS #: 146535-11-7. Molecular Formula: C16H14N2O2. Molecular Weight: 266.3 g/mol.
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