Product Name | Allopregnanolone |
Description |
Positive allosteric modulator of GABAA receptors |
Purity | >98% (HPLC); NMR (conforms) |
CAS No. | 516-54-1 |
Molecular Formula | C21H34O2 |
Molecular Weight | 318.5 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Inhibitor |
Solubility | May be dissolved in DMSO (32 mg/ml); or Ethanol (32 mg/ml) |
Source | Synthetic |
Appearance | White to off-white powder |
SMILES | CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C |
InChI | InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/m0/s1 |
InChIKey | AURFZBICLPNKBZ-SYBPFIFISA-N |
Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
Cite This Product | Allopregnanolone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-582) |
Alternative Names | (3α,5α)-3-Hydroxy-pregnan-20-one; (3α,5α)-tetrahydroprogesterone; 3-OH-DHP |
Research Areas | Cell Signaling, Neuroscience |
PubChem ID | 92786 |
Scientific Background | Allopprenanolone is a natural metabolite of progesterone that is devoid of any progestational activity. It acts and functions as a potent ligand of GABA type A receptor complexes in the CNS. It is a neuroactive steroid. Has recently been approved as a drug for postpartum depression by the FDA. |
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