Allopregnanolone

Positive allosteric modulator of GABAA receptors

Catalog No. SIH-582

0 out of 5 based on 0 customer ratings
CAS No. 516-54-1
Molecular Formula C21H34O2
SKU: SIH-582 Categories: ,

Clear
SIH-582-Allopregnanolone-Chemical-Structure.png
Product Name Allopregnanolone
Description

Positive allosteric modulator of GABAA receptors

Purity >98% (HPLC); NMR (conforms)
CAS No. 516-54-1
Molecular Formula C21H34O2
Molecular Weight 318.5
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility May be dissolved in DMSO (32 mg/ml); or Ethanol (32 mg/ml)
Source Synthetic
Appearance White to off-white powder
SMILES CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
InChI InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16-,17+,18-,19-,20-,21+/m0/s1
InChIKey AURFZBICLPNKBZ-SYBPFIFISA-N
Safety Phrases Classification:
Not a hazardous substance or mixture.

Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product Allopregnanolone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-582)

Biological Description

Alternative Names (3α,5α)-3-Hydroxy-pregnan-20-one; (3α,5α)-tetrahydroprogesterone; 3-OH-DHP
Research Areas Cell Signaling, Neuroscience
PubChem ID 92786
Scientific Background Allopprenanolone is a natural metabolite of progesterone that is devoid of any progestational activity. It acts and functions as a potent ligand of GABA type A receptor complexes in the CNS. It is a neuroactive steroid. Has recently been approved as a drug for postpartum depression by the FDA.

Product Images

<p>Chemical structure of Allopregnanolone (SIH-582), a Positive allosteric modulator of GABAA receptors</p>

Chemical structure of Allopregnanolone (SIH-582), a Positive allosteric modulator of GABAA receptors

Reviews

Reviews

There are no reviews yet.

Be the first to review “Allopregnanolone”

Your email address will not be published. Required fields are marked *