Baicalein

Lipoxygenase inhibitor

Catalog No. SIH-579

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CAS No. 491-67-8
Molecular Formula C15H10O5
SKU: SIH-579 Categories: ,

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SIH-579-Baicalein-Chemical-Structure.png
Product Name Baicalein
Description

Lipoxygenase inhibitor

Purity >98% (TLC); NMR (Conforms)
CAS No. 491-67-8
Molecular Formula C15H10O5
Molecular Weight 270.2
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility May be dissolved in DMSO (15 mg/ml)
Source Synthetic
Appearance Yellow to Yellow-green Crystalline powder
SMILES OC1=C(O)C(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1
InChI InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChIKey FXNFHKRTJBSTCS-UHFFFAOYSA-N
Safety Phrases Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product Baicalein (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-579)

Biological Description

Alternative Names 5,6,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one; Biacalein
Research Areas Alzheimer's Disease, Apoptosis, Cancer, Cell Cycle, Neurodegeneration, Neuroscience
PubChem ID 5281605
Scientific Background Baicalein is a flavonoid that is positive allosteric modulator of the GABA A Receptor (1). It also inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils (2).
References 1. Zhang S.Q., et al. (2013) J Neurosci. Res. 91(9): 1239-1246. 2. Zhu M., et al. (2004) J Biol Chem. 279(26): 26846-26857.

Product Images

<p>Chemical structure of Baicalein (SIH-579), a Lipoxygenase inhibitor. CAS #: 491-67-8. Molecular Formula: C15H10O5. Molecular Weight: 270.24 g/mol.</p>

Chemical structure of Baicalein (SIH-579), a Lipoxygenase inhibitor. CAS #: 491-67-8. Molecular Formula: C15H10O5. Molecular Weight: 270.24 g/mol.

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