BCTC

TRPV1 blocker

Catalog No. SIH-307

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CAS No. 393514-24-4
Molecular Formula C20H25ClN4O
SKU: SIH-307 Categories: ,

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SIH-307_BCTC_Chemical_Structure.png
Product Name BCTC
Description

TRPV1 blocker

Purity >98%
CAS No. 393514-24-4
Molecular Formula C20H25ClN4O
Molecular Weight 372.89
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 100 mM in DMSO and to 40 mM in ethanol
Source Synthetic
Appearance White Solid
SMILES CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl
InChI InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26)
InChIKey ROGUAPYLUCHQGK-UHFFFAOYSA-N
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Cite This Product BCTC (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-307)

Biological Description

Alternative Names 4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide
Research Areas Ion Channels, Neuroscience
PubChem ID 9929425
Scientific Background BCTC is an inhibitor of capsaicin- and acid-mediated currents at rat VR1. Thus it has effects on acute, inflammatory and neuropathic pain in rats (1, 2).
References 1. Pomonis J.D., et al. (2003) J Pharmacol Exp Ther. 306(1): 387-393.
2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386.

Product Images

<p>Chemical structure of BCTC (SIH-307), a TRPV1 blocker. CAS #: 393514-24-4. Molecular Formula: C20H25ClN4O. Molecular Weight: 372.89 g/mol.</p>

Chemical structure of BCTC (SIH-307), a TRPV1 blocker. CAS #: 393514-24-4. Molecular Formula: C20H25ClN4O. Molecular Weight: 372.89 g/mol.

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