Product Name | BCTC |
Description |
TRPV1 blocker |
Purity | >98% |
CAS No. | 393514-24-4 |
Molecular Formula | C20H25ClN4O |
Molecular Weight | 372.89 |
Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Storage Temperature | -20ºC |
Shipping Temperature | Shipped Ambient |
Product Type | Inhibitor |
Solubility | Soluble to 100 mM in DMSO and to 40 mM in ethanol |
Source | Synthetic |
Appearance | White Solid |
SMILES | CC(C)(C)C1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=C(C=CC=N3)Cl |
InChI | InChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26) |
InChIKey | ROGUAPYLUCHQGK-UHFFFAOYSA-N |
Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
Cite This Product | BCTC (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-307) |
Alternative Names | 4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide |
Research Areas | Ion Channels, Neuroscience |
PubChem ID | 9929425 |
Scientific Background | BCTC is an inhibitor of capsaicin- and acid-mediated currents at rat VR1. Thus it has effects on acute, inflammatory and neuropathic pain in rats (1, 2). |
References |
1. Pomonis J.D., et al. (2003) J Pharmacol Exp Ther. 306(1): 387-393. 2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386. |
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