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| Product Name | BML 259 |
| Description |
CDK5, p25 kinase inhibitor |
| Purity | >98% (TLC) |
| CAS No. | 267654-00-2 |
| Molecular Formula | C14H16N2OS |
| Molecular Weight | 260.4 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (30 mg/ml), dimethyl formamide (30 mg/ml) or 100% ethanol (0.25 mg/ml) |
| Source | Synthetic |
| Appearance | White solid |
| SMILES | CC(C)C1=CN=C(S1)NC(=O)CC2=CC=CC=C2 |
| InChI | InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17) |
| InChIKey | IGRZXNLKVUEFDM-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Bml 259 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-435) |
Biological Description
| Alternative Names | N-(5-Isopropylthiazol-2-yl)phenylacetamide |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 16760027 |
| Scientific Background | Bml 259 is a potent inhibitor of Cdk5/p25. It also inhibits Cdk2/cyclin E. |
| References | 1. Kaźmierczak A., Czapski G.A., Adamczyk A., Gajkowska B., & Strosznajder J.B. (2011) Neurochem. Int. 58(2): 206–214. |
Product Images
Chemical structure of BML 259 (SIH-435), a CDK5/p25 kinase inhibitor. CAS #: 267654-00-2. Molecular Formula: C14H16N2OS. Molecular Weight: 260.4 g/mol.
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