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| Product Name | BML-278 SIRT1 activator |
| Description |
SIRT1 activator |
| Purity | >98% (TLC); NMR (Conforms) |
| Molecular Formula | C24H25NO4 |
| Molecular Weight | 391.5 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in 5 mg/ml DMSO |
| Source | Synthetic |
| Appearance | Off-White Solid |
| Safety Phrases |
Classification: Caution – Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes |
| Cite This Product | Bml-278 SIRT1 activator (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-349) |
Biological Description
| Alternative Names | N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine |
| Research Areas | Cell Signaling |
| Scientific Background | A structurally novel activator of SIRT1 (EC150=1 µM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 µM respectively). Cell permeable. |
| References | 1. Mai A., et al. (2009) J. Med. Chem. 52: 5496. |
Product Images
Chemical structure of BML-278 SIRT1 activator (SIH-349), a SIRT1 activator. CAS #: N/A. Molecular Formula: C24H25NO4. Molecular Weight: 391.5 g/mol.
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