CAPE

NFkB Inhibitor

Catalog No. SIH-263

5 out of 5 based on 1 customer rating
CAS No. 104594-70-9
Molecular Formula C17H16O4
SKU: SIH-263 Categories: ,

Clear
SIH-263_CAPE_Chemical_Structure.png
Product Name CAPE
Description

NFkB Inhibitor

Purity >98%
CAS No. 104594-70-9
Molecular Formula C17H16O4
Molecular Weight 284.31
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 100 mM in DMSO, acetone, ethanol, methanol, acetonitrile
Source Synthetic
Appearance Off-White Solid
SMILES C1=CC=C(C=C1)CCOC(=O)/C=C/C2=CC(=C(C=C2)O)O
InChI InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
InChIKey SWUARLUWKZWEBQ-VQHVLOKHSA-N
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H315-H319-H335
Precautionary Phrases:
P261-P305 + P351 + P338
Cite This Product CAPE (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-263)

Biological Description

Alternative Names 2-Phenylethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate, Caffeic acid phenethyl ester
Research Areas Apoptosis, Cancer
PubChem ID 5281787
Scientific Background CAPE , an active component of propolis from honeybee hives is known to have antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral properties (1). It specifically inhibits NF-κB activation and inhibits the growth of transformed cells (1). Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.
References 1. Natarajan K., Singh S., Burke T.R., Grunberger D., Aggarwal B.B. (1996) Proc Natl Acad Sci USA. 93(17): 9090-9095.

Product Images

<p>Chemical structure of CAPE (SIH-263), a Inhibits NFkB activation. CAS #: 104594-70-9. Molecular Formula: C17H16O4. Molecular Weight: 284.31 g/mol.</p>

Chemical structure of CAPE (SIH-263), a Inhibits NFkB activation. CAS #: 104594-70-9. Molecular Formula: C17H16O4. Molecular Weight: 284.31 g/mol.

Reviews

1 review for CAPE

  1. 5 out of 5

    :

    Based on validation through cited publications.

Add a review

Your email address will not be published. Required fields are marked *