Cyclothiazide

AMPA receptor desensitization inhibitor

Catalog No. SIH-574

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CAS No. 2259-96-3
Molecular Formula C14H16ClN3O4S2
SKU: SIH-574 Categories: ,

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SIH-574-Cyclothiazide-Chemical-Structure.png
Product Name Cyclothiazide
Description

AMPA receptor desensitization inhibitor

Purity >98% (HPLC/TLC); NMR (conforms)
CAS No. 2259-96-3
Molecular Formula C14H16ClN3O4S2
Molecular Weight 389.9
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility May be dissolved in DMSO (35 mg/ml); or ethanol (9 mg/ml)
Source Synthetic
Appearance Off-white powder
SMILES NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C1CC2CC1C=C2
InChI InChI=1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)
InChIKey BOCUKUHCLICSIY-UHFFFAOYSA-N
Safety Phrases Hazard statement(s):
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s):
P260 Do not breathe dust/fume/gas/mist/vapours/spray
P264 Wash hands thoroughly after handling
P280 Wear protective gloves/protective clothing/eye protection/face protection
P302+352 IF ON SKIN: Wash with soap and water
P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P305+351+338 IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and
easy to do so - continue rinsing
P333+313 If skin irritation or a rash occurs: Get medical advice/attention
Cite This Product Cyclothiazide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-574)

Biological Description

Alternative Names 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide; LY-35483
Research Areas AMPA Receptors, Glutamate Receptors, Neuroscience, Neurotransmission, Neurotransmitter Receptors
PubChem ID 2910

Product Images

<p>Chemical structure of Cyclothiazide (SIH-574), a AMPA Receptor Modulator. CAS #: 2259-96-3. Molecular Formula: C14H16ClN3O4S2. Molecular Weight: 389.9 g/mol.</p>

Chemical structure of Cyclothiazide (SIH-574), a AMPA Receptor Modulator. CAS #: 2259-96-3. Molecular Formula: C14H16ClN3O4S2. Molecular Weight: 389.9 g/mol.

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