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| Product Name | Hypericin |
| Description |
Protein kinase C inhibitor |
| Purity | >98% |
| CAS No. | 548-04-9 |
| Molecular Formula | C30H16O8 |
| Molecular Weight | 504.45 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 10 mM in ethanol and to 50 mM in DMSO |
| Source | Synthetic |
| Appearance | Dark Red Solid |
| SMILES | CC1=CC(=C2C3=C4C5=C(C(=CC(=C5C2=O)O)O)C6=C7C4=C8C(=C13)C(=CC(=C8C(=O)C7=C(C=C6O)O)O)C)O |
| InChI | InChI=1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)2 |
| InChIKey | BTXNYTINYBABQR-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | Hypericin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-250) |
Biological Description
| Alternative Names | 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
| PubChem ID | 5281051 |
| Scientific Background | Hypericin is a naphtodianthrone that acts as an antibiotic and non-specific kinase inhibitor. It inhibits the action of dopamine beta-hydroxylase, leading to increased dopamine levels. Hypericin can also cause photosensitivity when ingested beyond threshold. And becase it also accumulates in cancerous tissues, it can be used as an indicator of cancerous cells (1, 2). |
| References |
1. Hopfner M., et al. (2003) Int J Colorectal Dis. 18(3): 239-247. 2. Agostinis, et al. (2002) Int J Biochem Cell Biol. 34: 221. |
Product Images
Chemical structure of Hypericin (SIH-250), a Protein kinase C inhibitor. CAS #: 548-04-9. Molecular Formula: C30H16O8 . Molecular Weight: 504.45 g/mol.
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