Isradipine

L-type Ca channel blocker

Catalog No. SIH-314

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CAS No. 75695-93-1
Molecular Formula C19H21N3O5
SKU: SIH-314 Categories: ,

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SIH-314_Isradipine_Chemical_Structure.png
Product Name Isradipine
Description

L-type Ca channel blocker

Purity >98%
CAS No. 75695-93-1
Molecular Formula C19H21N3O5
Molecular Weight 371.39
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 50 mM in DMSO and to 20 mM in ethanol
Source Synthetic
Appearance Yellow Crystalline Solid
SMILES CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC
InChI InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
InChIKey HMJIYCCIJYRONP-UHFFFAOYSA-N
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H302-H315-H317-H318-H335
Precautionary Phrases:
P261-P280-P305 + P351 + P338
Cite This Product Isradipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-314)

Biological Description

Alternative Names Isopropyl methyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, PN 200-110
Research Areas Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
PubChem ID 3784
Scientific Background Isradipine is a calcium channel blocker of the dihydropyridine class. It is usually used in the treatment of high blood pressure because of its anti-hypertensive properties in vivo (1). Recent studies suggest a potential use for Parkinson’s disease (2).
References 1. Wada Y., Satoh K., Taira N. (1985) J Cardiovasc Pharmacol. 7(1): 190-196.
2. Chan C.S., et al. (2007) Nature. 447: 1081-1086.

Product Images

<p>Chemical structure of Isradipine (SIH-314), a L-type Ca channel blocker. CAS #: 75695-93-1. Molecular Formula: C19H21N3O5. Molecular Weight: 371.39 g/mol.</p>

Chemical structure of Isradipine (SIH-314), a L-type Ca channel blocker. CAS #: 75695-93-1. Molecular Formula: C19H21N3O5. Molecular Weight: 371.39 g/mol.

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