Discovery through Partnership | Excellence through Quality
| Product Name | Leptomycin B |
| Description |
Nuclear export inhibitor |
| Purity | >99% (HPLC); NMR (Conforms) |
| CAS No. | 87081-35-4 |
| Molecular Formula | C33H48O6 |
| Molecular Weight | 540.7 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | May be dissolved into DMSO or ethanol. Use solutions made with DMSO within 24 hours. |
| Source | Synthetic |
| Appearance | Solution in ethanol (1 mg/ml) |
| SMILES | CCC(/C=C/[C@H]1OC(=O)C=C[C@@H]1C)=C/[C@H](C)CC=CC(C)=C[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)CC(C)=CC(O)=O |
| InChI | 1S/C33H48O6/c1-9-28(14-15-29-24(5)13-16-31(36)39-29)19-22(3)12-10-11-21(2)17-25(6)32(37)27(8)33(38)26(7)18-23(4)20-30(34)35/h10-11,13-17,19-20,22,24-27,29,33,38H,9,12,18H2,1-8H3,(H,34,35)/b11-10+,15- |
| InChIKey | YACHGFWEQXFSBS-NRQIOVFOSA-N |
| Safety Phrases |
Classification: B2 Flammable liquid - Flammable liquid D1B Toxic Material Causing Immediate and Serious Toxic Effects - Toxic by ingestion, Toxic by skin absorption Hazard statement(s): H225 Highly flammable liquid and vapour. H301 + H311 Toxic if swallowed or in contact with skin H315 Causes skin irritation. H319 Causes serious eye irritation. H331 Toxic if inhaled. H370 Causes damage to organs. Precautionary statement(s): P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ protective clothing. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P307 + P311 IF exposed: Call a POISON CENTER or doctor/ physician. |
| Cite This Product | Leptomycin B (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-534) |
Biological Description
| Alternative Names | Elactocin, LMB, Mantuamycin, NSC 364372 |
| Research Areas | Cancer, Cancer Growth Inhibitors |
| PubChem ID | 6917907 |
| Scientific Background | Leptomycin B is an inhibitor of nuclear export proteins. It is an anti-fungal, and anti-tumor cytotoxin. |
Product Images
Chemical structure of Leptomycin B (SIH-534), a Nuclear export inhibitor. CAS #: 87081-35-4. Molecular Formula: C33H48O6. Molecular Weight: 540.7 g/mol.
Powered by Bioz
Reviews
There are no reviews yet.