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| Product Name | LY 294002 |
| Description |
PI 3-Kinase inhibitor |
| Purity | >98% |
| CAS No. | 154447-36-6 |
| Molecular Formula | C19H17NO3•HCl |
| Molecular Weight | 343.81 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 5 mM in ethanol and to 25 mM in DMSO |
| Source | Synthetic |
| Appearance | White Crystalline Solid |
| SMILES | C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4 |
| InChI | InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2 |
| InChIKey | CZQHHVNHHHRRDU-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | LY 294002 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-252) |
Biological Description
| Alternative Names | 2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-one |
| Research Areas | Apoptosis, Cancer, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
| PubChem ID | 3973 |
| Scientific Background | LY294002 is a potent inhibitor of PI3Ks. It inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo (1). |
| References | 1. Vlahos, et al. (1994) J Biol Chem. 269: 5241. |
Product Images
Chemical structure of LY 294002 (SIH-252), a PI 3-Kinase inhibitor. CAS #: 154447-36-6. Molecular Formula: C19H17NO3 * HCl. Molecular Weight: 343.81 g/mol.
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Based on validation through cited publications.