Nifedipine

L-type Ca channel blocker

Catalog No. SIH-309

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CAS No. 21829-25-4
Molecular Formula C17H18N2O6
SKU: SIH-309 Categories: ,

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SIH-309_Nifedipine_Chemical_Structure.png
Product Name Nifedipine
Description

L-type Ca channel blocker

Purity >98%
CAS No. 21829-25-4
Molecular Formula C17H18N2O6
Molecular Weight 346.34
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 100 mM in DMSO
Source Synthetic
Appearance Yellow solid
SMILES CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
InChIKey HYIMSNHJOBLJNT-UHFFFAOYSA-N
Safety Phrases Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
R60 - May impair fertility
R61 - May cause harm to the unborn child
Hazard Phrases: H302
Cite This Product Nifedipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-309)

Biological Description

Alternative Names Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
Research Areas Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
PubChem ID 4485
Scientific Background Nifedipine is a dihydropyridine calcium channel blocker. It is used mainly as an antianginal, and hypertensive (1), but has other uses such as Raynaud’s phenomenon (2), premature labor, and painful spasms of the esophagus.
References 1. Dalal J.J., Griffiths B.E. and Henderson A.H. (1981) Br Heart J. 46(2): 230-231.
2. Thompson A.E., Pope J.E. (2005) Rheumatology. 44(2): 145-150.

Product Images

<p>Chemical structure of Nifedipine (SIH-309), a L-type Ca channel blocker. CAS #: 21829-25-4. Molecular Formula: C17H18N2O6. Molecular Weight: 346.34 g/mol.</p>

Chemical structure of Nifedipine (SIH-309), a L-type Ca channel blocker. CAS #: 21829-25-4. Molecular Formula: C17H18N2O6. Molecular Weight: 346.34 g/mol.

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