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| Product Name | Nitrendipine |
| Description |
L-type Ca channel blocker |
| Purity | >98% (TLC) |
| CAS No. | 39562-70-4 |
| Molecular Formula | C18H20N2O6 |
| Molecular Weight | 360.37 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (20mg/mL); or ethanol (10mg/mL) |
| Source | Synthetic |
| Appearance | Yellow Crystalline Solid |
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C |
| InChI | InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3 |
| InChIKey | PVHUJELLJLJGLN-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Caution: Substance not fully tested yet. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R62 - Possible risk of impaired fertility Hazard Phrases: H312-H332 Precautionary Phrases: P280 |
| Cite This Product | Nitrendipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-320) |
Biological Description
| Alternative Names | Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate |
| Research Areas | Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels |
| PubChem ID | 11931106 |
| Scientific Background | Nitrendipine is a dihydropyridine calcium channel blocker. It does so by binding effectively with the L-type calcium channels in smooth muscles thereby inactivating it and reducing the influx of calcium. |
| References | 1. Peterson B.Z., Tanada T.N., Catterall W.A. (1996) J Biol Chem. 271: 5293-5296. |
Product Images
Chemical structure of Nitrendipine (SIH-320), a L-type Ca channel blocker. CAS #: 39562-70-4. Molecular Formula: C18H20N2O6. Molecular Weight: 360.37 g/mol.
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