Nitrendipine

L-type Ca channel blocker

Catalog No. SIH-320

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CAS No. 39562-70-4
Molecular Formula C18H20N2O6
SKU: SIH-320 Categories: ,

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SIH-320_Nitrendipine_Chemical_Structure.png
Product Name Nitrendipine
Description

L-type Ca channel blocker

Purity >98% (TLC)
CAS No. 39562-70-4
Molecular Formula C18H20N2O6
Molecular Weight 360.37
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in DMSO (20mg/mL); or ethanol (10mg/mL)
Source Synthetic
Appearance Yellow Crystalline Solid
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C
InChI InChI=1S/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,16,19H,5H2,1-4H3
InChIKey PVHUJELLJLJGLN-UHFFFAOYSA-N
Safety Phrases Classification: Caution: Substance not fully tested yet.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Risk Phrases:
R62 - Possible risk of impaired fertility
Hazard Phrases:
H312-H332
Precautionary Phrases:
P280
Cite This Product Nitrendipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-320)

Biological Description

Alternative Names Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
Research Areas Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
PubChem ID 11931106
Scientific Background Nitrendipine is a dihydropyridine calcium channel blocker. It does so by binding effectively with the L-type calcium channels in smooth muscles thereby inactivating it and reducing the influx of calcium.
References 1.  Peterson B.Z., Tanada T.N., Catterall W.A. (1996) J Biol Chem. 271: 5293-5296.

Product Images

<p>Chemical structure of Nitrendipine (SIH-320), a L-type Ca channel blocker. CAS #: 39562-70-4. Molecular Formula: C18H20N2O6. Molecular Weight: 360.37 g/mol.</p>

Chemical structure of Nitrendipine (SIH-320), a L-type Ca channel blocker. CAS #: 39562-70-4. Molecular Formula: C18H20N2O6. Molecular Weight: 360.37 g/mol.

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