(R, S)-Niguldipine HCl

Ca2+ channel blocker

Catalog No. SIH-319

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CAS No. 119934-51-9
Molecular Formula C36H39N3O6•HCl
SKU: SIH-319 Categories: ,

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SIH-319_R-Niguldipine_HCl_Chemical_Structure.png
Product Name (R, S)-Niguldipine HCl
Description

Ca2+ channel blocker

Purity >98%
CAS No. 119934-51-9
Molecular Formula C36H39N3O6•HCl
Molecular Weight 646.18
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 10 mM in water
Source Synthetic
Appearance Yellow solid
Safety Phrases Classification: Caution: Substance not yet fully tested.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Cite This Product (R, S)-Niguldipine HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-319)

Biological Description

Alternative Names (R,S)-1,4-Dihydro-2,6-dimethyl-4-(3-n­itrophenyl)-3,5-pyridinedicarboxylic acid, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester hydrochloride
Research Areas Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
Scientific Background Niguldipine is a calcium channel blocker and an a1-adrenergic receptor antagonist.
References 1. Boer R., Grassegger A., Schudt C., Glossman H. (1999) Eur J Pharmacol. 172(2): 131-145.
2. Robinson J.P., Kendall D.A. (1990) Br J Pharmacol. 100(1): 3-4.

Product Images

<p>Chemical structure of (R, S)-Niguldipine HCl (SIH-319), a L-type Ca channel blocker. CAS #: 113317-61-6. Molecular Formula: C36H39N3O6.HCl. Molecular Weight: 646.18 g/mol.</p>

Chemical structure of (R, S)-Niguldipine HCl (SIH-319), a L-type Ca channel blocker. CAS #: 113317-61-6. Molecular Formula: C36H39N3O6.HCl. Molecular Weight: 646.18 g/mol.

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