SB-366791

TRPV1 blocker

Catalog No. SIH-321

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CAS No. 472981-92-3
Molecular Formula C16H14CINO2
SKU: SIH-321 Categories: ,

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SIH-321_SB-366791_Chemical_Structure.png
Product Name SB-366791
Description

TRPV1 blocker

Purity >98%
CAS No. 472981-92-3
Molecular Formula C16H14CINO2
Molecular Weight 287.75
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 10 mM in ethanol and to 100 mM in DMSO
Source Synthetic
Appearance White solid
SMILES COC1=CC=CC(=C1)NC(=O)/C=C/C2=CC=C(C=C2)Cl
InChI InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+
InChIKey RYAMDQKWNKKFHD-JXMROGBWSA-N
Safety Phrases Classification: Caution: Substance not fully tested yet.
Safety Phrases:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S24/25- Avoid contact with shin and eyes
Cite This Product SB-366791 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-321)

Biological Description

Alternative Names (2E)-3-(4-Chlorophenyl)-N-(3-methoxyphenyl)acrylamide, N-(3-Methoxyphenyl)-4-chlorocinnamide
Research Areas Ion Channels, Neuroscience
PubChem ID 667594
Scientific Background A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.
References 1. Gunthorpe M.J., et al. (2004) Neuropharmacology. 46(1): 133-149.

Product Images

<p>Chemical structure of SB-366791 (SIH-321), a TRPV1 blocker. CAS #: 472981-92-3. Molecular Formula: C16H14CINO2. Molecular Weight: 287.75 g/mol.</p>

Chemical structure of SB-366791 (SIH-321), a TRPV1 blocker. CAS #: 472981-92-3. Molecular Formula: C16H14CINO2. Molecular Weight: 287.75 g/mol.

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