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| Product Name | Simvastatin |
| Description |
HMG-CoA reductase inhibitor |
| Purity | >98% |
| CAS No. | 79902-63-9 |
| Molecular Formula | C25H38O5 |
| Molecular Weight | 418.57 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble to 75 mM in ethanol and 50 mM in DMSO |
| Source | Synthetic |
| Appearance | White solid |
| SMILES | CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C |
| InChI | InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15 |
| InChIKey | RYMZZMVNJRMUDD-HGQWONQESA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed, or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R62- Possible risk of impaired fertility |
| Cite This Product | Simvastatin (StressMarq Biosciences, Canada, Cat # SIH-257) |
Biological Description
| Alternative Names | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 54454 |
| Scientific Background | Simvastatin is a member of the drug class of statins, used for lowering cholersterol, thereby preventing cardiovascular disease. They have a powerful inhibitory effect on HMG-CoA reducatse (1). |
| References | 1. Alberts A.W. (1998) Am J Cardio. 62(15): 10J-15J. |
Product Images
Chemical structure of Simvastatin (SIH-257), a HMG-CoA reductase inhibitor. CAS #: 79902-63-9. Molecular Formula: C25H38O5. Molecular Weight: 418.57 g/mol.
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