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| Product Name | Sorafenib |
| Description |
Raf-1 kinase inhibitor |
| Purity | >99% |
| CAS No. | 284461-73-0 |
| Molecular Formula | C21H16ClF3N4O3 |
| Molecular Weight | 464.8 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble inDMSO (200mg/ml) or ethanol (3mg/ml) |
| Source | Synthetic |
| Appearance | Off white powder |
| SMILES | CNC(=O)c1cc(ccn1)Oc2ccc(cc2)NC(=O)Nc3ccc(c(c3)C(F)(F)F)Cl |
| InChI | InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31) |
| InChIKey | MLDQJTXFUGDVEO-UHFFFAOYSA-N |
| Safety Phrases |
Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Cite This Product | Sorafenib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-476) |
Biological Description
| Alternative Names | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; 4-methylbenzenesulfonic acid |
| Research Areas | Cell Signaling |
| PubChem ID | 216239 |
| Scientific Background | Sorafenib display inhibition of multiple kinase targets including, VEGFR, PDGFR, and Raf. |
| References | 1. Juan, L., et al. (2014) Environmental Toxic. Pharm. 38(2): 438–443. |
Product Images
Chemical structure of Sorafenib (SIH-476), a Raf-1 inhibitor (and other kinases). CAS #: 2884461-73-0. Molecular Formula: C21H16ClF3N4O3. Molecular Weight: 464.8 g/mol.
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Gi0CANTI :
Peut on avoir le certificat d’analyse du sorafenib Rf SIH 476 50mg Lot SS388296
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Brenda Knox :
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