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| Product Name | U-74389G |
| Description |
Lipid peroxidation blocker |
| Purity | >99% |
| CAS No. | 153190-29-5 |
| Molecular Formula | C37H50N6O2•C4H4O4 |
| Molecular Weight | 726.9 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in 25 mg/ml DMSO, and in 20 mg/ml in ethanol; Insoluble in water |
| Source | Synthetic |
| Appearance | White Solid |
| SMILES | C[C@]12CC=C3[C@H]([C@@H]1CC[C@@H]2C(=O)CN4CCN(CC4)C5=NC(=NC(=C5)N6CCCC6)N7CCCC7)CCC8=CC(=O)C=C[C@@]83C.C(=CC(=O)O)C(=O)O |
| InChI | InChI=1S/C37H50N6O2.CH4O3S/c1-36-13-11-27(44)23-26(36)7-8-28-29-9-10-31(37(29,2)14-12-30(28)36)32(45)25-40-19-21-42(22-20- |
| InChIKey | QZGBZPCDCMUFCW-FRVIMOPGSA-N |
| Safety Phrases |
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection |
| Cite This Product | U-74389G (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-205) |
Biological Description
| Alternative Names | 21-{4-[2,6-Di(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl}pregna-1,4,9(11)-triene-3,20-dione (2Z)-2-butenedioate (1:1) |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 104933 |
| Scientific Background | U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It prevents organ damage in intestinal cold storage, preservation and reperfusion injury (1-4). |
| References |
1. Ishizaki N., et al. (1997) Transplantation. 63: 202-208. 2. Perna A.M., et al. (1996) Pharmacol Res. 34: 25-31. 3. Palma-Vargas J.M., et al. (1996) J Surg Res. 66: 131-137. 4. Shoskes D.A., Xie Y., Gonzalez-Cadavid N.F. Transplantation. 63: 495-500. |
Product Images
Chemical structure of U-74389G (SIH-205), a Free radical scavenger. CAS #: 153190-29-5. Molecular Formula: C37H50N6O2 · C4H4O4 . Molecular Weight: 726.9 g/mol.
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