Verapamil HCl

L-type Ca channel blocker

Catalog No. SIH-308

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CAS No. 152-11-4
Molecular Formula C27H38N2O4•HCl
SKU: SIH-308 Categories: ,

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SIH-308_Verapamil_HCl_Chemical_Structure.png
Product Name Verapamil HCl
Description

L-type Ca channel blocker

Purity >98%
CAS No. 152-11-4
Molecular Formula C27H38N2O4•HCl
Molecular Weight 491.07
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble to 100 mM in ethanol and to 50 mM in water
Source Synthetic
Appearance White Solid
SMILES CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl
InChI InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,
InChIKey DOQPXTMNIUCOSY-UHFFFAOYSA-N
Safety Phrases Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed
R60 - May impair fertility
R61 - May cause harm to the unborn child
R68 - Possible risk of irreversible effects
Hazard Phrases:
H301-H311-H331
Precautionary Phrases:
P261-P280-P301 + P310-P311
Cite This Product Verapamil HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-308)

Biological Description

Alternative Names 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1)
Research Areas Calcium Channels, Ion Channels, Neuroscience, Voltage-Gated Calcium Channels
PubChem ID 62969
Scientific Background Verapamil is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and cluster headaches. Its mechanism is to block voltage-dependent calcium channels (1).
References 1. Livesley B., and Oram S. (1972) Br Med J. 2(5804): 50.

Product Images

<p>Chemical structure of Verapamil HCl (SIH-308), a L-type Ca channel blocker. CAS #: 152-11-4. Molecular Formula: C27H38N2O4.HCl. Molecular Weight: 491.07 g/mol.</p>

Chemical structure of Verapamil HCl (SIH-308), a L-type Ca channel blocker. CAS #: 152-11-4. Molecular Formula: C27H38N2O4.HCl. Molecular Weight: 491.07 g/mol.

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