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| Product Name | XAV939 |
| Description |
Tankyrase inhibitor |
| Purity | >98% (HPLC); NMR (conforms) |
| CAS No. | 284028-89-3 |
| Molecular Formula | C14H11F3N2OS |
| Molecular Weight | 312.3 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (25 mg/ml) |
| Source | Synthetic |
| Appearance | Off white powder |
| SMILES | c1cc(ccc1c2[nH]c(=O)c3c(n2)CCSC3)C(F)(F)F |
| InChI | InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20) |
| InChIKey | KLGQSVMIPOVQAX-UHFFFAOYSA-N |
| Safety Phrases |
Classification: D1B Toxic Material Causing Immediate and Serious Toxic Effects - Toxic by ingestion D2B Toxic Material Causing Other Toxic Effects Moderate eye irritant Hazard statement(s): H301 Toxic if swallowed. H319 Causes serious eye irritation. Precautionary statement(s): P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Cite This Product | XAV939 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-532) |
Biological Description
| Alternative Names | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Research Areas | Cell Signaling |
| PubChem ID | 2726824 |
| Scientific Background | XAV939 is a potent tankyrase (TNKS) inhibitor, as well as a Wnt inhibitor and beta-catenin inhibitor. |
Product Images
Chemical structure of XAV939 (SIH-532), a Tankyrase inhibitor. CAS #: 284028-89-3. Molecular Formula: C14H11F3N2OS. Molecular Weight: 312.3 g/mol.
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