ZM 306416

VEGFR kinase inhibitor

Catalog No. SIH-487

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CAS No. 690206-97-4
Molecular Formula C16H13ClFN3O2
SKU: SIH-487 Categories: ,

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SIH-487_ZM-306416_Chemical_Structure.png
Product Name ZM 306416
Description

VEGFR kinase inhibitor

Purity >98% (TLC)
CAS No. 690206-97-4
Molecular Formula C16H13ClFN3O2
Molecular Weight 333.7
Field of Use Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Properties

Storage Temperature -20ºC
Shipping Temperature Shipped Ambient
Product Type Inhibitor
Solubility Soluble in DMSO (3 mg/ml) or ethanol (1 mg/ml)
Source Synthetic
Appearance Off-white solid
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC
InChI InChI=1S/C16H13ClFN3O2/c1-22-14-6-10-13(7-15(14)23-2)19-8-20-16(10)21-12-4-3-9(17)5-11(12)18/h3-8H,1-2H3,(H,19,20,21)
InChIKey YHUIUSRCUKUUQA-UHFFFAOYSA-N
Safety Phrases Classification:
Not a hazardous substance or mixture.

Safety Phrases:
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Cite This Product ZM 306416 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-487)

Biological Description

Alternative Names ZM-306416
Research Areas Apoptosis, Cancer, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Tyrosine Kinase Inhibitors
PubChem ID 5329006
Scientific Background ZM 306416 is a potent and selective VEGF receptor tyrosine kinase inhibitor. Specifically, it inhibits Flk-1 (KDR) and Flt.
References 1. Hennequin L.F., et al. (1999) J. Med. Chem. 42(26): 5369–5389.
2. Kawai, T., et al. (2006) Neurosci. 141(3): 1209–1216.

Product Images

<p>Chemical structure of ZM 306416 (SIH-487), a VEGFR kinase inhibitor. CAS #: 690206-97-4. Molecular Formula: C16H13ClFN3O2. Molecular Weight: 333.7 g/mol.</p>

Chemical structure of ZM 306416 (SIH-487), a VEGFR kinase inhibitor. CAS #: 690206-97-4. Molecular Formula: C16H13ClFN3O2. Molecular Weight: 333.7 g/mol.

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