Discovery through Partnership | Excellence through Quality
| Product Name | Ionomycin |
| Description |
Ca2+ ionophore |
| Purity | >98% |
| CAS No. | 56092-81-0 |
| Molecular Formula | C41H70O9 |
| Molecular Weight | 709.01 |
| Field of Use | Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inducer |
| Solubility | Soluble to 10 mM in ethanol and to 10 mM in DMSO |
| Source | Synthetic |
| Appearance | Colorless Solid |
| SMILES | C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)O |
| InChI | InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23 |
| InChIKey | PGHMRUGBZOYCAA-OJFQOPKISA-N |
| Safety Phrases |
Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302 |
| Cite This Product | Ionomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-228) |
Biological Description
| Alternative Names | (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-22-{(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxo-10,16-docosadi enoic acid, Ionomycin calcium salt |
| Research Areas | Apoptosis, Cancer |
| PubChem ID | 6434517 |
| Scientific Background | Ionomycin is a calcium ionophore used in research to raise the intracellular level of calcium and as a tool to understand calcium transport across biological membranes. It is also used to stimulare the intracellular production of the cytokines interferon, perforin, IL-2 and IL-4. It is more specific than A23187. |
| References |
1. Holmes A.G. Watt M.J., Carey A.L. And Febbraio M.A. (2004) Metabolism. 53(11): 1492-1495. 2. Abramov A.Y., Duchen M.R. (2003) Cell Calcium. 33(2): 101-112. |
Product Images
Chemical structure of Ionomycin (SIH-228), a Ca2+ ionophore. CAS #: 56092-81-0. Molecular Formula: C41H70O9. Molecular Weight: 709.01 g/mol.
Powered by Bioz
StressMarq Biosciences :
Based on validation through cited publications.