Alzheimer's Disease

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  • Alpha Synuclein Protein

    Mouse Recombinant Alpha Synuclein Protein Monomers (Type 1)

    Catalog No. SPR-323

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    Expression System E. coli
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    SPR-323_Alpha-Synuclein-Protein-IHC-1.png
    Mouse alpha Synuclein monomers (SPR-323) form new alpha synuclein fibrils through the seeding activity of Type 1 alpha synuclein pre-formed fibrils (SPR-324) as shown by increased fluorescence intensity by Thioflavin T over time.SDS-Page of Mouse Recombinant Alpha Synuclein Protein Monomer (SPR-323)

  • Alpha Synuclein Protein

    Mouse Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-324

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    Expression System E. coli
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    SPR-324_Alpha-Synuclein-Protein-Preformed-Fibrils-ICC-IF-1.png
    IHC of mouse brain injected with alpha synuclein monomers and fibrilsIHC of mouse brain injected with alpha synuclein monomers and fibrilsIHC of Sprague-Dawley rat brain injected with Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324)Mouse hippocampal neurons treated with mouse alpha synuclein PFFs show phosphorylationTEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324).Mouse Type 1 alpha synuclein Pre-formed Fibrils (SPR-324) seed the formation of new alpha Synuclein fibrils from the pool of alpha synuclein monomers (SPR-323) as shown by increased fluorescence intensity by Thioflavin T over time.TEM of Type 1 mouse alpha synuclein Pre-formed Fibrils (SPR-324).SDS-Page of Type 1 Mouse Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-324)

  • Alpha Synuclein Protein

    Human Recombinant A53T Mutant Alpha Synuclein Protein Monomers (Type 1)

    Catalog No. SPR-325

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    Expression System E. coli
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    SPR-325_A53T-Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.Cisbio Total Alpha Synuclein AssayCisbio Alpha Synuclein Aggregation Assay

  • Alpha Synuclein Protein

    Human Recombinant A53T Mutant Alpha Synuclein Protein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-326

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    Expression System E. coli
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    SPR-326_A53T-Alpha-Synuclein-Preformed-Fibrils-Protein-ICC-IF-1.png
    TEM of A53T alpha synuclein Pre-formed fibrils (SPR-326).TEM of A53T alpha synuclein Pre-formed fibrils (SPR-326)Cisbio Alpha Synuclein Aggregation AssayCisbio Total Alpha Synuclein AssayThioflavin T emission curves show increased fluorescence (correlated to alpha synuclein aggregation) when A53T alpha synuclein Pre-formed fibrils (SPR-326) are combined with A53T alpha synuclein monomers (SPR-325). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.LDH assay shows effect of A53T alpha synuclein PFFs on mouse primary neuronsMTT assay effects of A53T alpha synuclein PFFs on mouse primary neurons

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Filaments

    Catalog No. SPR-450

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    Expression System E. coli
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    SPR-450_Alpha-Synuclein-Protein-Filaments-Protein-TEM-2.png
    TEM of Active Human Recombinant Alpha Synuclein Protein Filaments (SPR-450)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Oligomers (Dopamine HCL Stabilized)

    Catalog No. SPR-466

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    SPR-466_Alpha-Synuclein-Oligomers-Protein-TEM-1.png
    TEM of Human Recombinant Alpha Synuclein Oligomers (Dopamine HCL Stabilized) (SPR-466)HPLC of Alpha Synuclein Oligomers (SPR-466)LDH assay shows effect of alpha synuclein oligomers on mouse primary neuronsMTT assay shows effect of alpha synuclein oligomers on mouse primary neuronsCoomassie gel stain of alpha synuclein oligomer (SPR-466)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Oligomers (Epigallocatechin gallate (EGCG) Stabilized)

    Catalog No. SPR-469

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    SPR-469_Alpha-Synuclein-Oligomers-Protein-TEM-1.png
    Thioflavin T assay shows that EGCG-stabilzed alpha synuclein oligomers do not seed aggregation of alpha synuclein monomersSDS-PAGE of EGCG-stabilized alpha synuclein oligomers (SPR-469)Native SDS-PAGE of EGCG-stabilized alpha synuclein oligomers (SPR-469)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils: ATTO 594 (Type 1)

    Catalog No. SPR-322-A594

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    Expression System E. coli
    Tags ATTO 594
    SKU: SPR-322-A594 Category:

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    SPR-322-A594_Alpha-Synuclein-Protein-Protein-TEM-1.png
    Thioflavin T Assay for SPR-322-A594Human iPSC-derived neurons seeded with ATTO594 labelled alpha synuclein PFFs (SPR-322-A594)TEM of ATTO conjugated alpha syuclein pre-formed fibrils

  • Alpha Synuclein Protein

    Human Recombinant N-Terminal Acetylated Alpha Synuclein Monomers (Type 1)

    Catalog No. SPR-331

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    SPR-331_N-Terminal-Acetylated-Alpha-Synuclein-Monomer-Protein-Western-Blot-1.png
    Thioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Monomers (SPR-331)

  • Alpha Synuclein Protein

    Human Recombinant N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-332

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    Expression System E. coli
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    SPR-332_N-Terminal-Acetylated-Alpha-Synuclein-Fibril-Protein-TEM-1.png
    TEM of N-acetylated alpha synuclein PFFsThioflavin T Seeding Assay of N-Terminal Acetylated Alpha Synuclein Pre-formed Fibrils (SPR-332)

  • Alpha Synuclein Protein

    Rat Recombinant Alpha Synuclein Protein Monomers

    Catalog No. SPR-481

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    SPR-481_Alpha-Synuclein-Monomer-Protein-SDS-PAGE-1.png
    Thioflavin T Fluorescence Activity for Rat Alpha Synuclein Protein (SPR-481)

  • Alpha Synuclein Protein

    Rat Recombinant Alpha Synuclein Protein Pre-formed Fibrils

    Catalog No. SPR-482

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    SPR-482_Alpha-Synuclein-Fibrils-Protein-TEM-1.png
    TEM of Rat Alpha Synuclein Pre-formed Fibrils (PFFS) (SPR-482).Thioflavin T Fluorescence Activity for Rat Alpha Synuclein Protein (SPR-482)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable)

    Catalog No. SPR-484

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    Expression System E. coli
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    SPR-484_Alpha-Synuclein-Oligomers-Kinetcially-Stable-Protein-TEM-1.png
    Native PAGE of Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable) (SPR-484).Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Toxicity of Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable) (SPR-484).IHC of Human Recombinant Alpha Synuclein Oligomers (Kinetically Stable) (SPR-484).

  • Alpha Synuclein pSer129 Monomers

    Human Recombinant Alpha Synuclein Monomers phosphorylated at position 129

    Catalog No. SPR-520

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    SPR-520_Alpha-Synuclein-pSer129-Monomers-Protein-SDS-Page-1.png
    Dot Blot of Alpha Synuclein pSer129 Monomers (SPR-520)Mass Spec Bar Graph of Alpha Synuclein pSer129 Monomers (SPR-520)Thioflavin T assay of Alpha Synuclein pSer129 Monomers (SPR-520)

  • Alpha Synuclein pSer129 Pre-Formed Fibrils

    Human Recombinant Alpha Synuclein Pre-formed Fibrils phosphorylated at position 129

    Catalog No. SPR-521

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    SPR-521_Alpha-Synuclein-pSer129-Pre-Formed-Fibrils-Protein-TEM-1.png
    Sedimentation assay of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)Dot Blot of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)Mass Spec Bar Graph of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)Thioflavin T assay of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)TEM of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)AFM of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)SDS-Page of Alpha Synuclein pSer129 Pre-Formed Fibrils (SPR-521)

  • Alpha Synuclein S129A Mutant Monomers

    Human Recombinant Alpha Synuclein S129A Mutant Monomers

    Catalog No. SPR-505

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    Expression System E. coli
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    SPR-505_Alpha-Synuclein-S129A-Mutant-Monomers-Protein-SDS-Page-1.png
    Thioflavin T assay of Human Alpha Synuclein S129A Mutant Monomers Protein (SPR-505)