Cell Signaling

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  • Anti-SUR1 Antibody [N289/16 (Formerly sold as S289-16)]

    Mouse Anti-Rat SUR1 Monoclonal IgG1

    Catalog No. SMC-409

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    Species Reactivity Hu, Ms, Rt, Hm
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-409 Categories: ,

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    SMC-409_SUR1_Antibody_N289-16_ICC-IF_Human_Neuroblastoma-cells-SH-SY5Y-Composite-1.png
    Mouse Anti-SUR1 Antibody [N289/16] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Neuroblastoma cell line (SK-N-BE) (SMC-409)Mouse Anti-SUR1 Antibody [N289/16] used in Western Blot (WB) on Rat Brain Membrane (SMC-409)

  • Anti-SUR2A Antibody [N319A/14 (Formerly sold as S319A-14)]

    Mouse Anti-Mouse SUR2A Monoclonal IgG2A

    Catalog No. SMC-431

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    Species Reactivity Hu, Ms, Rt
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    SKU: SMC-431 Categories: ,

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    SMC-431_SUR2A_Antibody_N319A-14_ICC-IF_Human_Neuroblastoma-cells-SH-SY5Y-Composite-1.png
    Mouse Anti-SUR2A Antibody [N319A/14] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Neuroblastoma cell line (SK-N-BE) (SMC-431)Mouse Anti-SUR2A Antibody [N319A/14] used in Western Blot (WB) on Rat Brain Membrane (SMC-431)

  • Tafamidis

    Transthyretin Dissociation Inhibitor

    Catalog No. SIH-584

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    CAS No. 594839-88-0
    Molecular Formula C14H7Cl2NO3
    SKU: SIH-584 Categories: ,

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    SIH-584-Tafamidis-Chemical-Structure.png

  • Anti-Tau Antibody

    Rabbit Anti-Human Tau Polyclonal

    Catalog No. SPC-801

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    Species Reactivity Hu, Ms
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    SPC-801_Tau_Antibody_IHC_Human_Kidney_1.png
    Rabbit Anti-Tau Antibody used in Western blot (WB) on SH-SY5Y cell lysate (SPC-801)

  • Anti-Tau Antibody

    Rabbit Anti-Human Tau Polyclonal

    Catalog No. SPC-802

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    Species Reactivity Hu, Ms
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    SKU: SPC-802 Categories: ,

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    SPC-802_Tau_Antibody_IHC_Human_Brain-Cortex_1.png
    Rabbit Anti-Tau Antibody used in Western blot (WB) on SH-SY5Y cell lysate (SPC-802)

  • Anti-Tau Antibody

    Rabbit Anti-Human Truncated Tau Fragment (AA297-391) (dGAE) Polyclonal

    Catalog No. SPC-806

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    Species Reactivity Hu, Ms, Rt
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    SKU: SPC-806 Categories: ,

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    SPC-806_Tau_Antibody_WB_Mouse-Rat_Brain_1.png
    Rabbit Anti-Tau Antibody used in Dot blot (DB) on Recombinant Tau Monomers and Fibrils (SPC-806)

  • Anti-Tau Antibody [1D5]

    Mouse Anti-Human Tau Monoclonal IgG

    Catalog No. SMC-607

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    Species Reactivity Hu, Ms, Rt
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    SKU: SMC-607 Categories: ,

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    SMC-607_Tau_Antibody_1D5_ICC-IF_Human_iPSC-derived-neurons_1.png
    Mouse Anti-Tau Antibody [1D5] used in Western Blot (WB) on Human, Mouse Breast Cancer Cell line, Brain (SMC-607)Mouse Anti-Tau Antibody [1D5] used in Dot Blot (DB) on Human Recombinant Protein (SMC-607)

  • Anti-Tau Antibody [3D4]

    Mouse Anti-Human Tau Monoclonal IgG1

    Catalog No. SMC-608

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    Species Reactivity Hu, Ms, Rt
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    SKU: SMC-608 Categories: ,

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    SMC-608_Tau_Antibody_3D4_ICC-IF_Human_iPSC-derived-neurons_1.png
    Mouse Anti-Tau Antibody [3D4] used in Western Blot (WB) on Mouse Brain (SMC-608)Mouse Anti-Tau Antibody [3D4] used in Dot Blot (DB) on Human Recombinant Protein (SMC-608)

  • Anti-Tau Antibody (pSer202/ pThr205) [AH36]

    Rabbit Anti-Human Tau Monoclonal IgG

    Catalog No. SMC-601

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    Species Reactivity Hu, Ms
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    SKU: SMC-601 Categories: ,

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    SMC-601_Tau_Antibody_AH36_ICC-IF_Human_iPSC-derived-cortical-excitatory-neurons_1.png
    Rabbit Anti-Tau Antibody (pSer202/ pThr205) [AH36] used in Immunohistochemistry (IHC) on Mouse Brain slice (SMC-601)Rabbit Anti-Tau Antibody (pSer202/ pThr205) [AH36] used in Immunohistochemistry (IHC) on Mouse Brain slice (SMC-601)Rabbit Anti-Tau Antibody (pSer202/ pThr205) [AH36] used in Western Blot (WB) on Human iPSC-derived cortical neurons (SMC-601)Rabbit Anti-Tau Antibody (pSer202/ pThr205) [AH36] used in Dot Blot (DB) on E. Coli, Baculovirus (SMC-601)

  • Anti-Tau Antibody (pThr217) [15B7]

    Mouse Anti-Human Tau (pThr217) Monoclonal IgG1 Kappa

    Catalog No. SMC-615

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    Species Reactivity Hu, Ms, Rt
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    SKU: SMC-615 Categories: ,

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    SMC-615_Tau_Antibody_15B7_DB_Human-Mouse-Rat_Tau-Peptide-pThr217_1.png
    Mouse Anti-Tau Antibody (pThr217) [15B7] used in Dot Blot (DB) on Human, Mouse, Rat Tau 2N4R P301S (phospho & non-phospho) (SMC-615)Mouse Anti-Tau Antibody (pThr217) [15B7] used in Western Blot (WB) on Human, Mouse, Rat baculovirus expressed hTau 2N4R monomer (SMC-615)

  • Tau dGAE (297-391) AD-mimic Pre-formed Fibrils

    Human Recombinant Tau dGAE (297-391) AD-mimic Pre-formed Fibrils (fibrilized without heparin)

    Catalog No. SPR-502

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    Expression System E. coli
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    SPR-502_Tau-dGAE-297-391-AD-mimic-Pre-formed-Fibrils-Protein-TEM-1.png
    SDS-Page of Human Tau dGAE (297-391) AD-mimic Pre-formed Fibrils Protein (SPR-502)TEM of Human Tau dGAE (297-391) AD-mimic Pre-formed Fibrils Protein (SPR-502)TEM of Human Tau dGAE (297-391) AD-mimic Pre-formed Fibrils Protein (SPR-502)

  • Tau dGAE (297-391) Monomers

    Human Recombinant Tau dGAE (AA297-391) Monomers

    Catalog No. SPR-501

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    Expression System E. coli
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    SPR-501_Tau-dGAE-297-391-Monomers-Protein-SDS-Page-1.png
    TEM of Human Tau dGAE (297-391) Monomers Protein (SPR-501)

  • Tau Protein

    Human Recombinant Tau-441 (2N4R) P301S Mutant Protein Monomers

    Catalog No. SPR-327

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    Expression System E. coli
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    SPR-327_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in active tau monomers (SPR-327). A greater increase in fluorescence is seen when 50 μM active monomer (SPR-327) is combined with 10 μM of active fibrils (SPR-329 or SPR-330), as the active fibrils seed the formation of new fibrils from the pool of active monomers.

  • Tau Protein

    Human Recombinant Tau (K18) P301L Mutant Protein Monomers

    Catalog No. SPR-328

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    Expression System E. coli
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    SPR-328_Tau-Protein-Monomer-SDS-PAGE-1.png
    Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) in tau K18 P301L monomers (SPR-328) over time.

  • Tau Protein

    Human Recombinant Tau-441 (2N4R) P301S Mutant Protein Pre-formed Fibrils

    Catalog No. SPR-329

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    Expression System E. coli
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    SKU: SPR-329 Category:

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    SPR-329_Tau-Protein-Peformed-Fibrils-TEM-1.png
    TEM of recombinant Tau441 (2N4R), P301S mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) when tau Pre-formed fibrils (SPR-329) are combined with tau monomers (SPR-327). The Pre-formed fibrils seed the formation of new fibrils from a pool of monomers.SDS-PAGE of ~67 kDa Human Tau 2N4R P301S Pre-formed Fibrils (PFFs)

  • Tau Protein

    Human Recombinant Tau (K18) P301L Mutant Protein Pre-formed Fibrils

    Catalog No. SPR-330

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    Expression System E. coli
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    SPR-330_Tau-Preformed-Fibrils-Protein-IHC-1.png
    Comparison of AT8 (pSer202/pThr205) tau inclusions in P301L mice injected with K18 PFFs and negative control.TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)TEM of recombinant Tau (K18), P301L mutant Pre-formed Fibrils (PFFs)Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau Pre-formed fibrils (SPR-330). Tau Pre-formed fibrils (SPR-330) seed the formation of new tau fibrils when combined with tau monomers (SPR-327)SDS-PAGE of ~15 kDa Human Tau Protein K18/P301L Pre-formed Fibrils (SPR-330)