Neuroscience

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  • Anti-VPS35 Antibody [8A3]

    Mouse Anti-Human VPS35 Monoclonal IgG1

    Catalog No. SMC-604

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    Species Reactivity Hu, Ms, Rt
    Applications WB IHC ICC/IF FCM IP
    SKU: SMC-604 Categories: ,

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    SMC-604_VPS35_Antibody_8A3_IHC_Mouse_Kidney_1.png
    Mouse Anti-VPS35 Antibody [8A3] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human A549 cells (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human A549 WT, VPS35 KO cells (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Immunoprecipitation (IP) on Human A549 cells (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Immunoprecipitation (IP) on Human A549 cells (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Western Blot (WB) on Human, Mouse A549, MEF (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Western Blot (WB) on Human SH-SY5Y (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Immunoprecipitation (IP) on Human A549 cells (SMC-604)Mouse Anti-VPS35 Antibody [8A3] used in Immunoprecipitation (IP) on Mouse embryonic fibroblast (SMC-604)

  • Anti-VPS35 Antibody [10A8]

    Mouse Anti-Human VPS35 Monoclonal IgG2a

    Catalog No. SMC-605

    5 out of 5 based on 1 customer rating
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    Species Reactivity Hu, Ms, Rt
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    SKU: SMC-605 Categories: ,

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    SMC-605_VPS35_Antibody_10A8_IHC_Human_Thyroid-Cancer_1.png
    Mouse Anti-VPS35 Antibody [10A8] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human A549 cells (SMC-605)Mouse Anti-VPS35 Antibody [10A8] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human A549 WT, VPS35 KO cells (SMC-605)Mouse Anti-VPS35 Antibody [10A8] used in Immunoprecipitation (IP) on Human A549 cells (SMC-605)Mouse Anti-VPS35 Antibody [10A8] used in Immunoprecipitation (IP) on Human A549 cells (SMC-605)Mouse Anti-VPS35 Antibody [10A8] used in Western Blot (WB) on Human, Mouse A549, MEF (SMC-605)Mouse Anti-VPS35 Antibody [10A8] used in Western Blot (WB) on Human SH-SY5Y (SMC-605)Mouse Anti-VPS35 Antibody [10A8] used in Immunoprecipitation (IP) on Human A549 cells (SMC-605)

  • Anti-VPS35 Antibody [11H10]

    Mouse Anti-Human VPS35 Monoclonal IgG2b

    Catalog No. SMC-606

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    Species Reactivity Hu, Ms, Rt
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    SMC-606_VPS35_Antibody_11H10_IHC_Human_Intestinal-Cancer_1.png
    Mouse Anti-VPS35 Antibody [11H10] used in Immunoprecipitation (IP) on Human A549 cells (SMC-606)Mouse Anti-VPS35 Antibody [11H10] used in Immunoprecipitation (IP) on Human A549 cells (SMC-606)Mouse Anti-VPS35 Antibody [11H10] used in Western Blot (WB) on Human, Mouse A549, MEF (SMC-606)Mouse Anti-VPS35 Antibody [11H10] used in Immunoprecipitation (IP) on Human A549 cells (SMC-606)Mouse Anti-VPS35 Antibody [11H10] used in Immunoprecipitation (IP) on Mouse embryonic fibroblast (SMC-606)

  • MOLECULAR SIGNATURE® VPS35 Kit

    Colorimetric measurement of VPS35

    Catalog No. SKT-141

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    Species Reactivity Human, Mouse, Rat
    Sample Types Cell Lysate, Tissue
    SKU: SKT-141 Categories: ,

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    SKT-141_VPS35_Kit_Typical_Standard_Curve
    Graph of the Linearity Recovery for the VPS35 Kit - SKT-141Graph of the VPS35 Determination of WT-A549 vs KN-549 Lysates Graph for the VPS35 Kit MOLECULAR SIGNATURE® - SKT-141

  • Anti-Wnt5a Antibody

    Rabbit Anti-Human Wnt5a Polyclonal

    Catalog No. SPC-737

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    Species Reactivity Hu
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    SPC-737_Wnt5a_Antibody_IHC_Human_Thyroid-Carcinoma_10X_1.png
    Rabbit Anti-Wnt5a Antibody used in Western blot (WB) on Cervical cancer cell line (HeLa) lysate (SPC-737)

  • YM-58483

    CRAC channel  blocker

    Catalog No. SIH-606

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    CAS No. 223499-30-7
    Molecular Formula C15H9F6N5OS
    SKU: SIH-606 Categories: ,

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    SIH-606-YM-58483-Chemical-Structure.png

  • (R, S)-Niguldipine HCl

    Ca2+ channel blocker

    Catalog No. SIH-319

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    CAS No. 119934-51-9
    Molecular Formula C36H39N3O6•HCl
    SKU: SIH-319 Categories: ,

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    SIH-319_R-Niguldipine_HCl_Chemical_Structure.png

  • 2-APB

    TRP blocker

    Catalog No. SIH-316

    5 out of 5 based on 1 customer rating
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    CAS No. 524-95-8
    Molecular Formula C14H16BNO
    SKU: SIH-316 Categories: ,

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    SIH-316_2-APB_Chemical_Structure.png

  • A-803467

    NaV1.8 blocker

    Catalog No. SIH-304

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    CAS No. 944261-79-4
    Molecular Formula C19H16ClNO4
    SKU: SIH-304 Categories: ,

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    SIH-304_A-803467_Chemical_Structure.png

  • A-967079

    TRPA1 blocker

    Catalog No. SIH-301

    5 out of 5 based on 1 customer rating
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    CAS No. 1170613-55-4
    Molecular Formula C12H14FNO
    SKU: SIH-301 Categories: ,

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    SIH-301_A-967079_Chemical_Structure.png

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Monomers (Type 2)

    Catalog No. SPR-316

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    Expression System E. coli
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    SKU: SPR-316 Category:

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    SPR-316_Alpha-Synuclein-Protein-Monomer-Protein-SDS-Page-1.png
    Alpha Synuclein monomers (SPR-316) do not form new alpha synuclein fibrils when combined with Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by a limited increase in fluorescence intensity by Thioflavin T over time.Alpha Synuclein Monomer RT-QuiC AssayΑlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.LDH assay shows effect of alpha synuclein monomers on mouse primary neuronsMTT assay shows effects of alpha synuclein monomers on mouse primary neurons

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2)

    Catalog No. SPR-317

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    Expression System E. coli
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    SPR-317_Alpha-Synuclein-Preformed-Fibrils-Protein-TEM-4.png
    TEM of Type 2 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-317)Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.SDS-Page of Type 2 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-317)Type 2 alpha synuclein Pre-formed fibrils (SPR-317) do not seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) at the same rate as Type 1 alpha synuclein Pre-formed fibrils (SPR-322) as shown by lower fluorescence intensity values of Thioflavin T over time.Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)LDH assay shows effect of alpha synuclein PFFs on mouse primary neuronsMTT assay effects of alpha synuclein PFFs on mouse primary neurons

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Protein Monomers (Type 1)

    Catalog No. SPR-321

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    Expression System E. coli
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    SKU: SPR-321 Category:

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    SPR-321_Alpha-Synuclein-Protein-Monomer-Thioflavin-T-assay-1.png
    SDS-Page of huma alpha synuclein monomer (SPR-321)

  • Alpha Synuclein Protein

    Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

    Catalog No. SPR-322

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    Expression System E. coli
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    SKU: SPR-322 Category:

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    SPR-322_Alpha-Synuclein-Protein-Preformed-Fibrils-Protein-TEM-7.png
    Αlpha Synuclein Oligomers Have Distinct Secondary Structure Differences Compared to Fibrils.Alpha Synuclein Pre-formed Fibrils (PFF), Type 1 (cat#SPR-322) and Type 2 (cat#SPR-317) do have small secondary structure differences.StressMarq’s Alpha Synuclein PFFs (red) cat#SPR-322, were shown to be taken up by SH-SY5Y cells and transmitted to neuronal iPSCs within 14 days.SDS-Page of Type 1 Human Recombinant Alpha Synuclein Protein Pre-formed Fibrils (SPR-322)Type 1 alpha synuclein Pre-formed Fibrils (SPR-322) seed the formation of new alpha synuclein fibrils from the pool of alpha synuclein monomers (SPR-321) as shown by increased fluorescence intensity by Thioflavin T over time.Immunocytochemistry/Immunofluorescence of Human Alpha Synuclein Protein Protein (SPR-322)Mouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFsMouse neurocortical primary cells seeded with fluorescently-labelled alpha synuclein PFFs cause endogenous alpha synuclein phosphorylationTEM of Type 1 Alpha Synuclein Pre-formed Fibrils (PFFs) (SPR-322)IHC of Sprague-Dawley rat brain injected with Type 1 human alpha synuclein Pre-formed Fibrils (SPR-322)Primary rat hippocampal neurons show lewy body inclusion formation when treated with Type 1 Alpha Synuclein Protein Pre-formed Fibrils (SPR-322) (D-F), but not when treated with Type 2 Alpha Synuclein Protein Pre-formed Fibrils (SPR-317) (A-C).Toxicity results comparing Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 2) and Active Human Recombinant Alpha Synuclein Pre-formed Fibrils (Type 1)

  • Amlodipine

    L-type Ca channel blocker

    Catalog No. SIH-315

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    CAS No. 111470-99-6
    Molecular Formula C20H25ClN2O5•C6H5SO3H
    SKU: SIH-315 Categories: ,

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    SIH-315_Amlodipine_Chemical_Structure.png

  • AP-18

    TRPA1 blocker

    Catalog No. SIH-310

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    CAS No. 55224-94-7
    Molecular Formula C11H12ClNO
    SKU: SIH-310 Categories: ,

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    SIH-310_AP-18_Chemical_Structure.png