Cell membrane markers are key tools for enabling researchers to determine the location of novel proteins within the cell by reliably labeling the outer cell membrane.

The cell membrane, also known as the plasma membrane or cytoplasmic membrane, is the barrier that separates the internal components (cytoplasm and nucleus) of the cell from the extracellular environment. The cell membrane is made of a glycerophospholipid bilayer. Embedded within the cell membrane are numerous transmembrane proteins (channels, proton pumps, receptors), cholesterol, glycolipids, carbohydrates, and other proteins.

The cell membrane functions to protect the inside of the cell. It is semi-permeable, thereby allowing the movement of small molecules like oxygen and carbon dioxide to cross easily, while water and other polar molecules pass more slowly. The cell membrane controls the movement of charge particles (ie. ions) and large molecules (ie. glucose) through the opening and closing of channels. The cell membrane also functions to shape the cell by interacting with the extracellular matrix and anchoring the internal cytoskeleton filaments.

The cell membrane also performs endocytosis and exocytosis. Endocytosis allows the cell to take in external substances by surrounding them with the cell membrane. This process forms vesicles that are then pinched off from the cell membrane, and move through the cell. Exocytosis is the reverse of endocytosis. A vesicle will dock with the cell membrane, merging the vesicle membrane with the cell membrane, thereby releasing the material previously stored within the vesicle to the extracellular environment.

StressMarq provides a variety of membrane markers to aid in the study of neuroscience, including monoclonal antibodies, polyclonal antibodies, and antibody conjugates.

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