Sodium channels are transmembrane ion channels that selectively conduct sodium ions across the cell membrane. They are present in excitable cells such as neurons and myocytes where they contribute to the influx of sodium cations, and the resulting rising phase of the action potential.

There are two main classes:

• Ligand-gated Sodium Channels
• Voltage-gated Sodium Channels

Sodium channel blockers are small molecules which block the flow of sodium ions through channels either from the extracellular or intracellular side of the channel. Sodium channel blockers are used to treat cardiac arrhythmia.

Ion channel research requires a great diversity of life science products. We are dedicated to developing cutting edge research products to aid in the study of ion channels, including monoclonal antibodies, polyclonal antibodies, antibody conjugates, and small molecule inhibitors.

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